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Titolo:
BLOCKADE OF SPONTANEOUS POSTTRAINING PERFORMANCE IMPROVEMENT IN MICE BY NMDA ANTAGONISTS
Autore:
MELAN C; EICHENLAUB D; UNGERER A; MESSIER C; DESTRADE C;
Indirizzi:
UNIV TOULOUSE 3,LAB NEUROBIOL & COMPORTEMENT,BAT 4R3,118 RTE NARBONNEF-31062 TOULOUSE FRANCE UNIV STRASBOURG 1,PSYCHOPHYSIOL LAB,CNRS,URA 1295 F-67070 STRASBOURG FRANCE UNIV OTTAWA,SCH PSYCHOL OTTAWA ON K1N 6N5 CANADA UNIV BORDEAUX 1,LAB NEUROSCI COMPORTEMENTALES & COGNIT,CNRS,URA 339 BORDEAUX FRANCE
Titolo Testata:
Pharmacology, biochemistry and behavior
fascicolo: 4, volume: 56, anno: 1997,
pagine: 589 - 594
SICI:
0091-3057(1997)56:4<589:BOSPPI>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
METHYL-D-ASPARTATE; GLUTAMYL-L-ASPARTATE; SCHEDULE-CONTROLLED BEHAVIOR; AVOIDANCE-LEARNING TASK; LONG-TERM POTENTIATION; RECEPTOR ANTAGONISTS; ACID RECEPTOR; HIPPOCAMPAL STIMULATION; MEMORY; CPP;
Keywords:
MEMORIZATION; CRF; GAMMA-L-GLUTAMYL-L-ASPARTATE; 3-(2-CARBOXYPIPERAZINE-4-YL)PROPYL-1-PHOSPHONATE; N-METHYL-D-ASPARTATE RECEPTOR; MOUSE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
43
Recensione:
Indirizzi per estratti:
Citazione:
C. Melan et al., "BLOCKADE OF SPONTANEOUS POSTTRAINING PERFORMANCE IMPROVEMENT IN MICE BY NMDA ANTAGONISTS", Pharmacology, biochemistry and behavior, 56(4), 1997, pp. 589-594

Abstract

We investigated the effects of immediate post training systemic administration of gamma-L-glutamyl-L-aspartate (gamma-LGLA) and 3-(2-carboxypiperazine-4-yl)-propyl-1-ph (CPP), antagonists at the N-merhyl-D-aspartate receptor, in a lever-press task in two inbred strains of mice. When retention performance was tested in control animals 24 h after partial acquisition of the task, BALB/c mice exhibited a spontaneous performance improvement whereas C57BL/6J mice did not. gamma-LGLA at doses of 2.5 and 25 mu mol/kg and CPP at doses ranging between 0.025 and 2.5 mu mol/kg blocked the spontaneous performance improvement found in BALB/c mice but had no apparent effects on the retention performance of C57BL/6J mice. These data suggest that retention impairment induced by CPP and gamma-LGLA in BALB/c mice results from an interference withposttraining memory processes. (C) 1997 Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 16:46:25