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Titolo:
SUPERIOR TEMPORAL GYRUS AND PLANUM TEMPORALE IN SCHIZOPHRENIA - A SELECTIVE REVIEW
Autore:
PEARLSON GD;
Indirizzi:
JOHNS HOPKINS UNIV,SCH MED,DEPT PSYCHIAT,DIV PSYCHIAT NEUROIMAGING,600 N WOLFE ST,MEYER 3-166 BALTIMORE MD 21287 JOHNS HOPKINS UNIV,SCH MED,DEPT PSYCHIAT & BEHAV SCI BALTIMORE MD 21287
Titolo Testata:
Progress in neuro-psychopharmacology & biological psychiatry
fascicolo: 8, volume: 21, anno: 1997,
pagine: 1203 - 1229
SICI:
0278-5846(1997)21:8<1203:STGAPT>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; FIRST-EPISODE SCHIZOPHRENIA; HUMAN AUDITORY-CORTEX; MAGNETIC-RESONANCE; ENTORHINAL CORTEX; BLOOD-FLOW; NEURONAL-ACTIVITY; THOUGHT-DISORDER; RHESUS-MONKEY; CORTICAL AFFERENTS;
Keywords:
SUPERIOR TEMPORAL GYRUS; PLANUM TEMPORALE; HETEROMODAL NEOCORTEX; AND SCHIZOPHRENIA;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
104
Recensione:
Indirizzi per estratti:
Citazione:
G.D. Pearlson, "SUPERIOR TEMPORAL GYRUS AND PLANUM TEMPORALE IN SCHIZOPHRENIA - A SELECTIVE REVIEW", Progress in neuro-psychopharmacology & biological psychiatry, 21(8), 1997, pp. 1203-1229

Abstract

1. The normal structure of the superior temporal gyrus (STG) has beenelucidated from human and non-human primate research. This brain region is structurally complex, contains several distinct cellular regionsand the area known as the planum temporale. 2. The STG connects with heteromodal neocortical regions and temporolimbic areas. 3. Functionalstudies of the normal STG in animals and in humans, using electrophysiology and PET/fMRI, emphasize the STG's role as part of a cortical network important in the interpretation, production and self-monitoring of language. 4. There is evidence for structural abnormalities of the STG in schizophrenia including both volume reductions and disturbancesof normal asymmetries. 5. Functional studies of this region in schizophrenic patients, including measurements of evoked potentials and of bloodflow, are abnormal, especially when patients perform language tasks or experience hallucinations. 6. This structural and functional pathology in the STG probably represents one example of a more general disruption in schizophrenia of the neocortical network of which this region is an essential part. This disturbance may be closely associated with the symptoms of formal thought disorder and of auditory hallucinations commonly seen in the disorder.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 20:18:24