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Titolo:
SIDE-EFFECTS OF ADJUNCT LIGHT THERAPY IN PATIENTS WITH MAJOR DEPRESSION
Autore:
MULLER MJ; SEIFRITZ E; HATZINGER M; HEMMETER U; HOLSBOERTRACHSLER E;
Indirizzi:
UNIV BASEL,HOSP PSYCHIAT,DEPRESS RES UNIT,WILHELM KLEIN STR 27 CH-4025 BASEL SWITZERLAND UNIV BASEL,HOSP PSYCHIAT,DEPRESS RES UNIT CH-4025 BASEL SWITZERLAND
Titolo Testata:
European archives of psychiatry and clinical neuroscience
fascicolo: 5, volume: 247, anno: 1997,
pagine: 252 - 258
SICI:
0940-1334(1997)247:5<252:SOALTI>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEASONAL AFFECTIVE-DISORDER; BRIGHT LIGHT; NONSEASONAL DEPRESSION; SLEEP-DEPRIVATION; PHOTOTHERAPY; MELATONIN; HYPOTHESIS; SEROTONIN;
Keywords:
BRIGHT-LIGHT THERAPY; SIDE EFFECTS; MAJOR DEPRESSION; ADJUNCT THERAPY;
Tipo documento:
Article
Natura:
Periodico
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
M.J. Muller et al., "SIDE-EFFECTS OF ADJUNCT LIGHT THERAPY IN PATIENTS WITH MAJOR DEPRESSION", European archives of psychiatry and clinical neuroscience, 247(5), 1997, pp. 252-258

Abstract

Adjunct bright-light therapy has been suggested to augment antidepressant drug treatment in patients with non-seasonal major depression. Side effects of the combined therapy have not been investigated thus far. Therefore, somatic complaints and side effects of combined therapy were evaluated in 28 patients with major depression (DSM-III-R) randomly assigned to either trimipramine or trimipramine and serially appliedadjunct bright-light therapy. Response rates were comparable in both treatment groups and rates of newly emergent side effects during treatment were generally low. The most prominent unfavourable side effects of adjunct bright-light therapy as compared with trimipramine monotherapy were aggravated sedation, persisting restlessness, emerging sleep disturbance and decreased appetite as well as the worsening of vertigo. Discriminant analysis revealed that the combination of trimipramine with bright light results in a different side effect profile compared with drug monotherapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 01:26:13