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Titolo:
PLASMA-LEVELS OF CYTOKINES AND SOLUBLE CYTOKINE RECEPTORS DURING TREATMENT WITH HALOPERIDOL
Autore:
POLLMACHER T; HINZESELCH D; FENZEL T; KRAUS T; SCHULD A; MULLINGTON J;
Indirizzi:
MAX PLANCK INST PSYCHIAT,INST CLIN,KRAEPELINSTR 10 D-80804 MUNICH GERMANY
Titolo Testata:
The American journal of psychiatry
fascicolo: 12, volume: 154, anno: 1997,
pagine: 1763 - 1765
SICI:
0002-953X(1997)154:12<1763:POCASC>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
TUMOR-NECROSIS-FACTOR; INTERLEUKIN-2 RECEPTORS; CLOZAPINE; SLEEP; SCHIZOPHRENIA;
Tipo documento:
Article
Natura:
Periodico
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
T. Pollmacher et al., "PLASMA-LEVELS OF CYTOKINES AND SOLUBLE CYTOKINE RECEPTORS DURING TREATMENT WITH HALOPERIDOL", The American journal of psychiatry, 154(12), 1997, pp. 1763-1765

Abstract

Objective: Clozapine increases the levels of cytokines and soluble cytokine receptors. The authors investigated whether haloperidol has similar effects. Method: Rectal temperature, white blood cell counts, andplasma levels of cytokines and soluble cytokine receptors were assessed before and during 6 weeks of haloperidol treatment in 10 psychiatric patients. Results: Haloperidol at mean doses of 7.0 mg/day (SD = 3.4), 6.9 mg/day (SD = 3.4), and 5.0 mg/day (SD = 3.1) at the end of the 1st, 2nd, and 6th weeks of treatment, respectively, did not affect rectal temperature, white blood cell counts, or plasma level of interleukin-l receptor antagonist, interleukin-6, tumor necrosis factor-alpha (TNF-alpha), soluble TNF receptor p55 or p75, or soluble interleukin-2 receptor. Conclusions: Haloperidol is unlikely to confound the resultsof studies investigating disease-related alterations In the levels ofa broad range of cytokines and soluble cytokine receptors in schizophrenia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 11:23:10