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Titolo:
INDUCTION OF LABOR WITH USE OF A FOLEY CATHETER AND EXTRAAMNIOTIC CORTICOSTEROIDS
Autore:
BARKAI G; COHEN SB; KEES S; LUSKY A; MARGALIT V; MASHIACH S; SCHIFF E;
Indirizzi:
CHAIM SHEBA MED CTR,DEPT OBSTET & GYNECOL IL-52621 TEL HASHOMER ISRAEL TEL AVIV UNIV,SACKLER FAC MED IL-69978 TEL AVIV ISRAEL
Titolo Testata:
American journal of obstetrics and gynecology
fascicolo: 5, volume: 177, anno: 1997,
pagine: 1145 - 1148
SICI:
0002-9378(1997)177:5<1145:IOLWUO>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN AMNION CELLS; RANDOMIZED TRIAL; PROSTAGLANDIN-E2; GLUCOCORTICOIDS; CORTISOL; BALLOON; CERVIX; FLUID;
Keywords:
CORTICOSTEROIDS; INDUCTION OF LABOR; FOLEY CATHETER;
Tipo documento:
Article
Natura:
Periodico
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
G. Barkai et al., "INDUCTION OF LABOR WITH USE OF A FOLEY CATHETER AND EXTRAAMNIOTIC CORTICOSTEROIDS", American journal of obstetrics and gynecology, 177(5), 1997, pp. 1145-1148

Abstract

OBJECTIVE: Our purpose was to examine the hypothesis that corticosteroids, when administered extraamniotically, can enhance the labor process and reduce the induction-to-delivery interval. STUDY DESIGN: A double-blind, randomized study was conducted on 98 women with a gestational age of 36 to 42 weeks, an unfavorable cervix, and medical indications for delivery, who were assigned to receive either 20 mg of dexamethasone in saline solution (study group, n = 50) or saline solution only (control group, n = 48) administered extraamniotically through an intracervical inflated Foley balloon catheter. The net effect of steroids was assessed with use of multivariant logistic regression analysis. RESULTS: The mean time intervals between induction of labor to the active phase and between induction of labor to delivery were significantly shorter in the study group compared with those of the control group (7.8 +/- 3.1 hours vs 9.9 +/- 3.9 hours, p < 0.03, 11.9 +/- 3.0 hours vs14.5 +/- 4.8 hours. p < 0.01, respectively). Those not receiving steroids were at a 3.2 higher risk of having a longer time interval of induction to delivery (95% confidence interval 1.1 to 9.5). The general success rate in achieving vaginal delivery was, however, similar between the groups. CONCLUSIONS: Induction of labor with use of an intracervical Foley balloon catheter and extraamniotic corticosteroids reduces the time interval from induction of labor to delivery. This may indicate a possible role for corticosteroids in the parturition process.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/07/20 alle ore 07:57:16