Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
ADVANCES IN THE STUDY OF ANIONIC AND CATI ONIC AMINO-ACID-TRANSPORT
Autore:
AVILACHAVEZ E; TORRESYTORRES N; TOVARPALACIO AR;
Indirizzi:
INST NACL NUTR SALVADOR ZUBIRAN,DEPT FISIOL NUTR,VASCO QUIROGA 15 MEXICO CITY 14000 DF MEXICO INST NACL NUTR SALVADOR ZUBIRAN,DEPT FISIOL NUTR MEXICO CITY 14000 DFMEXICO
Titolo Testata:
Revista de Investigacion Clinica
fascicolo: 5, volume: 49, anno: 1997,
pagine: 411 - 424
SICI:
0034-8376(1997)49:5<411:AITSOA>2.0.ZU;2-6
Fonte:
ISI
Lingua:
SPA
Soggetto:
XENOPUS-LAEVIS OOCYTES; ECOTROPIC RETROVIRUS RECEPTOR; MOUSE PERITONEAL-MACROPHAGES; BORDER MEMBRANE-VESICLES; AFFINITY GLUTAMATE TRANSPORTER; NA+-INDEPENDENT TRANSPORT; MONOCLONAL-ANTIBODY 4F2; CELL-SURFACE ANTIGEN; RABBIT KIDNEY CORTEX; L-ARGININE TRANSPORT;
Keywords:
AMINO ACID TRANSPORT; SYSTEM XAG(-); SYSTEM XC(-); SYSTEM RBAT; SYSTEM Y(+)L; SYSTEM Y(+)L; SYSTEM Y(+); SYSTEM B(O+); SYSTEM BO+;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
141
Recensione:
Indirizzi per estratti:
Citazione:
E. Avilachavez et al., "ADVANCES IN THE STUDY OF ANIONIC AND CATI ONIC AMINO-ACID-TRANSPORT", Revista de Investigacion Clinica, 49(5), 1997, pp. 411-424

Abstract

In mammalian cells, amino acids are taken up by different transport systems present in the plasma membrane. The transport systems were originally characterized by kinetic and competition studies. However, it was difficult to assign specific amino acids to specific transport systems. With recent advances in molecular biology, it has been possible to identify the specific transporter proteins for specific amino acids. In this review we describe the anionic and cationic amino acid transport systems reported at the molecular level. The anionic amino acids are movilized mainly by the XAG(-) and Xc(-) systems which are important in the inactivation of glutamatergic nervous transmission in the brain and for the synthesis of glutathione, respectively. Four isoforms of the XAG(-) system in the brain belong to the family of Na+ dependentamino acid transporters. Transport systems for cationic amino acids also recognize zwitterionic substrates, and the better characterized systems at the present time are y(+), y(+)L, b(o,+) and B-o,B-+. The regulation of the entrance of cationic amino acid such as arginine, lysine, and ornithine to the cell is important in the biosynthesis of nitric oxide, creatine, carnitine, and polyamines. An inherited defect associated to b(o,+) system is cysteinuria.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/21 alle ore 07:36:19