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Titolo:
THE EFFECT OF PREGNANCY ON CYCLOSPORINE LEVELS IN RENAL-ALLOGRAFT PATIENTS
Autore:
THOMAS AG; BURROWS L; KNIGHT R; PANICO M; LAPINSKI R; LOCKWOOD CJ;
Indirizzi:
MT SINAI MED CTR,DEPT OBSTET & GYNECOL,1176 5TH AVE,BOX 1170 NEW YORKNY 10029 MT SINAI SCH MED,DEPT OBSTET GYNECOL & REPROD SCI NEW YORK NY 00000 MT SINAI SCH MED,DEPT SURG,DIV ABDOMINAL TRANSPLANTAT NEW YORK NY 00000 NYU,SCH MED,DEPT OBSTET & GYNECOL NEW YORK NY 00000
Titolo Testata:
Obstetrics and gynecology
fascicolo: 6, volume: 90, anno: 1997,
pagine: 916 - 919
SICI:
0029-7844(1997)90:6<916:TEOPOC>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSPLANT RECIPIENTS;
Tipo documento:
Article
Natura:
Periodico
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
A.G. Thomas et al., "THE EFFECT OF PREGNANCY ON CYCLOSPORINE LEVELS IN RENAL-ALLOGRAFT PATIENTS", Obstetrics and gynecology, 90(6), 1997, pp. 916-919

Abstract

Objective: To assess the effects of pregnancy on cyclosporine levels in six renal allograft patients. Methods: Maternal demographic, laboratory, clinical, and perinatal outcome data were recorded in six pregnant women with previous renal allografts receiving cyclosporine immunosuppression. The cyclosporine and serum creatinine levels were measuredbefore pregnancy, during each trimester, and postpartum. Results: Themean (standard deviation [SD]) maternal age was 29.1 (3.8) years. Parity ranged from 9 to 3. Mean serum creatinine levels tended to be lower during pregnancy than before or after, as did the mean cyclosporine levels. After adjusting for dose, five of six patients had declines incyclosporine level during pregnancy. The mean (SD) gestational age atdelivery was 37.5 (2.8) weeks with a mean (SD) birth weight of 2837 (538) g. Conclusion: Pregnancy in patients with renal allografts can lead to a substantial decline in cyclosporine levels. (C) 1997 by The American College of Obstetricians and Gynecologists.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 12:12:41