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Titolo:
WHEN ARE PLACEBO-CONTROLLED TRIALS NO LONGER APPROPRIATE
Autore:
BRODY BA;
Indirizzi:
BAYLOR COLL MED,CTR MED ETH & HLTH POLICY,1 BAYLOR PLAZA HOUSTON TX 77030
Titolo Testata:
Controlled clinical trials
fascicolo: 6, volume: 18, anno: 1997,
pagine: 602 - 612
SICI:
0197-2456(1997)18:6<602:WAPTNL>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Keywords:
PLACEBO CONTROL GROUPS; RESEARCH ETHICS; THROMBOLYTIC AGENTS; EQUIPOISE; INFORMED CONSENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
B.A. Brody, "WHEN ARE PLACEBO-CONTROLLED TRIALS NO LONGER APPROPRIATE", Controlled clinical trials, 18(6), 1997, pp. 602-612

Abstract

This paper presents a standard for assessing the validity of placebo-controlled trials in circumstances in which such trials might be unjustly denying appropriate therapies to members of the control group. This standard categorizes the types of risks that tan or cannot be imposed upon consenting research subjects in such control groups. The paper also shows how needed research can be conducted while respecting the proposed ethical standard. Both the problem and the proposed standard are illustrated by reference to the major trials of the thrombolytic agents. (C) Elsevier Science Inc. 1997.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 13:16:59