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Titolo:
Utility of immunophenotypic and immunogenotypic analysis in the study of necrotic lymph nodes
Autore:
Vega, F; Lozano, MD; Alcalde, J; Pardo-Mindan, FJ;
Indirizzi:
Univ Navarra Clin, Dept Pathol, E-31080 Pamplona, Spain Univ Navarra ClinPamplona Spain E-31080 Pathol, E-31080 Pamplona, Spain Univ Navarra, Fac Med, Clin Univ, Dept Otolaryngol, E-31080 Pamplona, Spain Univ Navarra Pamplona Spain E-31080 Otolaryngol, E-31080 Pamplona, Spain
Titolo Testata:
VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY
fascicolo: 3, volume: 434, anno: 1999,
pagine: 245 - 248
SICI:
0945-6317(199903)434:3<245:UOIAIA>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTIGEN PRESERVATION; MALIGNANT-LYMPHOMA; INFARCTION; TISSUES;
Keywords:
immunohistochemistry; gene rearrangement; lymph node necrosis; malignant lymphoma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Lozano, MD Univ Navarra Clin, Dept Pathol, Apartado 4209, E-31080 Pamplona, Spain Univ Navarra Clin Apartado 4209 Pamplona Spain E-31080 , Spain
Citazione:
F. Vega et al., "Utility of immunophenotypic and immunogenotypic analysis in the study of necrotic lymph nodes", VIRCHOWS AR, 434(3), 1999, pp. 245-248

Abstract

We report a case of complete lymph node necrosis. No specific aetiology could be determined by morphology, but a B lymphoid population and clonal rearrangement of the immunoglobulin heavy chain gene were demonstrated in immunophenotypic and immunogenotypic studies performed using DNA extracted fromparaffin embedded necrotic tissue. In the setting of lymph node necrosis, we suggest that immunohistochemical and gene rearrangement studies may provide additional diagnostic information.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 13:49:52