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Titolo:
Molecular epidemiological studies of veterinary arboviral encephalitides
Autore:
Weaver, SC; Powers, AM; Brault, AC; Barrett, ADT;
Indirizzi:
Univ Texas, Med Branch, Ctr Trop Dis, Galveston, TX 77555 USA Univ Texas Galveston TX USA 77555 , Ctr Trop Dis, Galveston, TX 77555 USA Univ Texas, Med Branch, Dept Pathol, Galveston, TX 77555 USA Univ Texas Galveston TX USA 77555 h, Dept Pathol, Galveston, TX 77555 USA
Titolo Testata:
VETERINARY JOURNAL
fascicolo: 2, volume: 157, anno: 1999,
pagine: 123 - 138
SICI:
1090-0233(199903)157:2<123:MESOVA>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
VENEZUELAN EQUINE ENCEPHALITIS; HIGHLANDS J-VIRUS; OLIGONUCLEOTIDE FINGERPRINT ANALYSIS; COMPLETE NUCLEOTIDE-SEQUENCE; JAPANESE ENCEPHALITIS; ENCEPHALOMYELITIS VIRUS; MONOCLONAL-ANTIBODIES; ANTIGENIC ANALYSIS; EXPERIMENTAL-INFECTION; PHYLOGENETIC ANALYSIS;
Keywords:
arbovirus; encephalitis; mosquito; epidemiology; phylogeny;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
113
Recensione:
Indirizzi per estratti:
Indirizzo: Weaver, SC Univ Texas, Med Branch, Ctr Trop Dis, Galveston, TX 77555 USA Univ Texas Galveston TX USA 77555 Dis, Galveston, TX 77555 USA
Citazione:
S.C. Weaver et al., "Molecular epidemiological studies of veterinary arboviral encephalitides", VET J, 157(2), 1999, pp. 123-138

Abstract

Recent studies using molecular genetic approaches have made important contributions to our understanding of the epidemiology of veterinary arboviral encephalitides. Viruses utilizing avian enzootic hosts, such as Western equine encephalitis virus (WEEV) and North American Eastern equine encephalitis virus (EEEV), evolve as relatively few, highly conserved genotypes that extend over wide geographic regions; viruses utilizing mammalian hosts with more limited dispersal evolve within multiple genotypes, each geographically restricted. Similar findings have been reported for Australian alphaviruses. This difference may be related to vertebrate host relationships and therelative mobility of mammals and avians. Whereas EEEV and Venezualan equine encephalitis virus (VEEV) utilize small mammalian hosts in the tropics, most WEEV genotypes probably utilize avian hosts in both North and South America. The ability of mobile, infected avian hosts to disperse alphaviruses may result in continual mixing of virus populations, and thus limit diversification. This high degree of genetic conservation is also exhibited by EEEand Highlands J viruses in North America, where passerine birds serve as amplifying hosts in enzootic transmission foci. Most equine arboviral pathogens, including EEEV, WEEV and Japanese encephalitis virus (JEV), occur in a naturally virulent enzootic state and requireonly appropriate ecological conditions to cause epizootics and epidemics. However; VEE epizootics apparently require genetic changes to convert avirulent enzootic strains into distinct epizootic serotypes. All of these arboviruses have the potential to cause severe disease of veterinary and human health importance, and further molecular epidemiological studies will undoubtedly improve our ability to understand and control future emergence.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 07:32:18