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Titolo:
Cognitive impairment and cerebral atrophy in "heavy drinkers"
Autore:
Ratti, MT; Soragna, D; Sibilla, L; Giardini, A; Albergati, A; Savoldi, F; Bo, P;
Indirizzi:
Univrolvia, Ctr Alcohol Abuse & Alcoholism, Neurol Inst C Mondino, Dept Neu Univ Pavia Pavia Italy I-27100 coholism, Neurol Inst C Mondino, Dept Neu
Titolo Testata:
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
fascicolo: 2, volume: 23, anno: 1999,
pagine: 243 - 258
SICI:
0278-5846(199902)23:2<243:CIACAI>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
DETOXIFIED ALCOHOLICS; REMOTE MEMORY; BRAIN; DEFICITS; DRINKING; MEN;
Keywords:
alcoholism; cerebral atrophy; cognitive functions; frontal robe;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Ratti, MT Univrolvia, Ctr Alcohol Abuse & Alcoholism, Neurol Inst C Mondino, Dept Neu Univ Pavia Via Palestro 3 Pavia Italy I-27100 Mondino, Dept Neu
Citazione:
M.T. Ratti et al., "Cognitive impairment and cerebral atrophy in "heavy drinkers"", PROG NEUR-P, 23(2), 1999, pp. 243-258

Abstract

1. Aim of the work was to verify the following three hypotheses in alcoholics: a) right hemisphere, b) diffuse brain deficit; c) anterior brain deficit, by means of a neuropsychological and a neuroradiological assessment.2. 15 alcoholic right-hand male subjects and 15 matched controls were enrolled in the study.3. Specifically designed neuropsychological testing was performed to investigate logical abilities, selective attention and memory.4. Neurological investigation was performed by a standard CT scan to assess the degree and localization of brain damage.5. Alcoholics performed worse than controls on some neuropsychological tests, i.e. Attention Matrices Test, Verbal Judgement Test, Forward Digit Span, Story Recall and Remote Memory Test. The analysis of variance adjusted bythe attentional score showed no significant differences between alcoholicsand controls.6. Neuroradiological data showed a preminnent and a more frequent atrophy of the frontal region.7. No correlations emerged between neuropsychological and neuroradiological data.8. In conclusion, the hypothesis of anterior brain deficit seems to be confirmed by our study.

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Documento generato il 21/01/20 alle ore 07:42:00