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Titolo:
Clinic-daytime blood pressure difference and cardiovascular damage
Autore:
Guida, L; Iannuzzi, R; Crivaro, M; Gaeta, I; Pasanisi, F; Celentano, A; Marotta, T; Ferrara, LA;
Indirizzi:
Univ Naples Federico II, Dept Clin & Expt Med, I-80131 Naples, Italy Univ Naples Federico II Naples Italy I-80131 Med, I-80131 Naples, Italy
Titolo Testata:
JOURNAL OF HYPERTENSION
fascicolo: 3, volume: 17, anno: 1999,
pagine: 331 - 337
SICI:
0263-6352(199903)17:3<331:CBPDAC>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEFT-VENTRICULAR MASS; WHITE COAT HYPERTENSION; NERVOUS-SYSTEM ACTIVITY; LABORATORY STRESSORS; MENTAL STRESS; REACTIVITY; RESPONSES; ADOLESCENTS; STABILITY; EXERCISE;
Keywords:
clinic-daytime blood pressure difference; cardiovascular reactivity; cold pressor test; isometric exercise; left ventricular hypertrophy; carotid wall thickening;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Ferrara, LA Univles,les Federico II, Dept Clin & Expt Med, Via S Pansini 5, I-80131 Nap Univ Naples Federico II Via S Pansini 5 Naples Italy I-80131
Citazione:
L. Guida et al., "Clinic-daytime blood pressure difference and cardiovascular damage", J HYPERTENS, 17(3), 1999, pp. 331-337

Abstract

Objective To investigate whether the clinic-daytime blood pressure difference can provide information on vascular reactivity to stress comparable to that of simple noninvasive stimuli such as a cold presser test and isometric exercise, and whether there is any relationship between this blood pressure difference and noninvasive measurements of the left ventricular mass andcarotid arterial wall. Design Patients with newly discovered, never-treated, sustained hypertension were included in the study after a 1 month run-in, during which time their blood pressure was measured three times at 2 week intervals. Methods Blood pressure was measured by a noninvasive procedure at rest andduring a cold presser test and an isometric exercise. The difference was calculated for systolic, diastolic and mean blood pressure as resting minus daytime ambulatory blood pressure. Parameters of the posterior wall and septal thickness of the left ventricle, aortic root and left atrium were studied by M-mode echocardiography. Carotid wall thickness and diameter were measured using ultrasound. Results The 90 patients enrolled in the study were divided into tertiles of clinic-daytime blood pressure difference. The composition of the groups differed in sex, since the majority of women were in the highest tertile, but was comparable for age, body mass index, renin-aldosterone axis and lipidand carbohydrate metabolism. Blood pressure responses to cold and isometric exercise were more pronounced in patients in the lowest tertile of blood pressure difference. No intergroup differences were detected in echocardiographic parameters of ventricular (left ventricular mass, tertiles I-III: 46.5 +/- 10, 42.3 +/- 8, 44.8 +/- 13 g/m(2.7), respectively) and carotid (intima-media thickness, tertiles I-III 0.58 +/- 0.1, 0.54 +/- 0.1, 0.62 +/- 0.1 mm, respectively) structure. Conclusions The present study indicates that the clinic-daytime blood pressure difference provides different information on cardiovascular reactivitycompared with that obtained from the cold presser test and isometric exercise. Moreover, it does not seem to have any relationship with ventricular hypertrophy and/or carotid wall thickening. J Hypertens 1999, 17:331-337 (C)Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 22:06:52