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Titolo:
Spontaneous course of symptoms in primary sclerosing cholangitis: Relationships with biochemical and histological features
Autore:
Olsson, R; Broome, U; Danielsson, A; Hagerstrand, I; Jarnerot, G; Loof, L; Prytz, H; Ryden, BO;
Indirizzi:
Sahlgrens Univ Hosp, Dept Med, S-41345 Gothenburg, Sweden Sahlgrens Univ Hosp Gothenburg Sweden S-41345 S-41345 Gothenburg, Sweden Huddinge Hosp, S-14186 Huddinge, Sweden Huddinge Hosp Huddinge Sweden S-14186 nge Hosp, S-14186 Huddinge, Sweden Umea Univ Hosp, S-90185 Umea, Sweden Umea Univ Hosp Umea Sweden S-90185Umea Univ Hosp, S-90185 Umea, Sweden Med Ctr Hosp, Orebro, Sweden Med Ctr Hosp Orebro SwedenMed Ctr Hosp, Orebro, Sweden Univ Uppsala Hosp, Uppsala, Sweden Univ Uppsala Hosp Uppsala SwedenUniv Uppsala Hosp, Uppsala, Sweden Univ Lund Hosp, Dept Pathol, S-22185 Lund, Sweden Univ Lund Hosp Lund Sweden S-22185 sp, Dept Pathol, S-22185 Lund, Sweden Linkoping Univ Hosp, S-58185 Linkoping, Sweden Linkoping Univ Hosp Linkoping Sweden S-58185 , S-58185 Linkoping, Sweden
Titolo Testata:
HEPATO-GASTROENTEROLOGY
fascicolo: 25, volume: 46, anno: 1999,
pagine: 136 - 141
SICI:
0172-6390(199901/02)46:25<136:SCOSIP>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
6
Recensione:
Indirizzi per estratti:
Indirizzo: Olsson, R Sahlgrens Univ Hosp, Dept Med, S-41345 Gothenburg, Sweden Sahlgrens Univ Hosp Gothenburg Sweden S-41345 thenburg, Sweden
Citazione:
R. Olsson et al., "Spontaneous course of symptoms in primary sclerosing cholangitis: Relationships with biochemical and histological features", HEP-GASTRO, 46(25), 1999, pp. 136-141

Abstract

An analysis was made of the symptom diaries of 65 patients with primary sclerosing cholangitis (PSC) who recorded their symptoms of itching, pain andfever during a 3 year period. Symptoms occurred in 84 % of the patients, with considerable individual variations in symptom load. Symptoms were usually intermittent. "Itching only" and "pain only" were the most frequent episode features. Most episodes lasted only 1-2 days. Fever seemed to be the most embarrassing symptom. Apartfrom close correlations between pruritus and serum ALP levels, there were no significant correlations between the symptom load and serum biochemistryor eleven different histological features. Even daily symptoms over a period of several months could disappear spontaneously. We conclude that most symptom episodes in PSC are mono-symptomatic and brief. Biochemical or histological data do not predict the appearance of symptoms.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 11:53:36