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Titolo:
Supraclavicular masses: Results of a series of 309 cases biopsied by fine needle aspiration
Autore:
Ellison, E; LaPuerta, P; Martin, SE;
Indirizzi:
Univ So Calif, Dept Pathol, Los Angeles, CA 90033 USA Univ So Calif Los Angeles CA USA 90033 Pathol, Los Angeles, CA 90033 USA Univ So Calif, Dept Med, Los Angeles, CA USA Univ So Calif Los Angeles CAUSA So Calif, Dept Med, Los Angeles, CA USA
Titolo Testata:
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
fascicolo: 3, volume: 21, anno: 1999,
pagine: 239 - 246
SICI:
1043-3074(199905)21:3<239:SMROAS>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
LYMPH-NODE METASTASES; CARCINOMA; DIAGNOSIS; NECK;
Keywords:
lymphadenopathy; supraclavicular; fine needle aspiration; Virchow's node;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Martin, SE Univ So Calif, Dept Pathol, NOR 2420,Hlth Sci Campus, Los Angeles, CA 90033 Univ So Calif NOR 2420,Hlth Sci Campus Los Angeles CA USA 90033
Citazione:
E. Ellison et al., "Supraclavicular masses: Results of a series of 309 cases biopsied by fine needle aspiration", HEAD NECK, 21(3), 1999, pp. 239-246

Abstract

Background. The purpose of this study was to determine the current distribution of diseases resulting in supraclavicular swelling or lymphadenopathy as diagnosed by fins needle aspiration (FNA) biopsy. Methods: Supraclavicular aspirates in this retrospective 5-year study froma large public hospital were classified as neoplastic, infectious, inflammatory, reactive, and nondiagnostic. Results: Malignancy was present in 55% of the 309 aspirates (47% metastatic, 8% lymphoma). Age was most predictive of malignancy (32% for age less than or equal to 41 years, 68% for age >40 years). Lymphoma occurred equally in both groups, but the lymphoma:metastasis ratio was much higher in younger patients (1:1.6 for age less than or equal to 41 years versus 1:11 for age >40 years). Ethnic origin was related to tumor type, metastatic uterine cervical carcinoma being most frequent in Hispanics, and lymphoma in Caucasians. Primary oropharyngeal sites were unusual; most malignancies originatedin the lung, breast, or cervix. Left or right side did not discriminate for either the presence or type of tumor. The 43 aspirates from human immunodeficiency virus (HIV) positive (+) patients were predominantly inflammatory, infectious, or reactive; lymphoma was infrequent (7%). Overall, 39 patients had mycobacterial infection; aspirate smears or culture were positive in19. Three other FNAs grew Staphylococcus aureus and one stained for Cryptococcus. Aspirates were not informative in 24 cases (8%). The sensitivity ofFNA for malignancy was 97%, specificity was 98%, and positive predictive value 98%. Conclusion: Aspiration biopsy is an excellent diagnostic tool for supraclavicular masses. Patients over 40 years old are likely to have metastatic malignancy, from breast, lung, or infradiaphragmatic sites. Aspirates with inflammation and those from HIV+ patients should undergo extensive culture. (C) 1999 John Wiley & Sons, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 20:27:02