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Titolo:
Dietary vitamin A and teratogenic risk: European Teratology Society discussion paper
Autore:
Dolk, HM; Nau, H; Hummler, H; Barlow, SM;
Indirizzi:
Univ London London Sch Hyg & Trop Med, Environm Epidemiol Unit, London WC1E Univ London London Sch Hyg & Trop Med London England WC1E 7HT ondon WC1E Vet Med Univ, Dept Food Toxicol, Hannover, Germany Vet Med Univ HannoverGermany niv, Dept Food Toxicol, Hannover, Germany
Titolo Testata:
EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY
fascicolo: 1, volume: 83, anno: 1999,
pagine: 31 - 36
SICI:
0301-2115(199903)83:1<31:DVAATR>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANS-RETINOIC ACID; BETA-CAROTENE; CYNOMOLGUS MONKEY; A SUPPLEMENTATION; 13-CIS-RETINOIC ACID; EXPOSURE; PHARMACOKINETICS; METABOLISM; PLASMA; CONSUMPTION;
Keywords:
vitamin A; teratogenicity; epidemiology; animal studies; public health advice;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
52
Recensione:
Indirizzi per estratti:
Indirizzo: Barlow, SM 8 Harrington Rd, Brighton BN1 6RE, E Sussex, England 8 Harrington Rd Brighton E Sussex England BN1 6RE sex, England
Citazione:
H.M. Dolk et al., "Dietary vitamin A and teratogenic risk: European Teratology Society discussion paper", EUR J OB GY, 83(1), 1999, pp. 31-36

Abstract

This review discusses the predictive value of animal models in assessment of possible risk from excess vitamin A consumption during pregnancy and thehuman evidence concerning risk of congenital malformations from excess vitamin A in the diet, consumed either as a constituent of normal foods or in the form of dietary vitamin supplements. Other sources of exposure to vitamin A include medicines (dermal and oral preparations) and cosmetics, but these are not further considered here. Conservative estimates of the likely safe intake of vitamin A during pregnancy are available, based on results from scientific research to date. However, current uncertainties are such that further research is needed to more clearly define intakes which may be onthe borderline between those which are beneficial and those which may posea risk to the developing embryo and fetus. (C) 1999 Elsevier Science Ireland Ltd All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 02:51:25