Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Incidence and distribution pattern of pelvic and paraaortic lymph node metastasis in patients with stages IB, IIA, and IIB cervical carcinoma treatedwith radical hysterectomy
Autore:
Sakuragi, N; Satoh, C; Takeda, N; Hareyama, H; Takeda, M; Yamamoto, R; Fujimoto, T; Oikawa, M; Oikawa, M; Fujino, T; Fujimoto, S;
Indirizzi:
Hokkaidoapanv, Sch Med, Dept Obstet & Gynecol, Sapporo, Hokkaido 0608638, J Hokkaido Univ Sapporo Hokkaido Japan 0608638 Sapporo, Hokkaido 0608638, J
Titolo Testata:
CANCER
fascicolo: 7, volume: 85, anno: 1999,
pagine: 1547 - 1554
SICI:
0008-543X(19990401)85:7<1547:IADPOP>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
ENDOMETRIAL CARCINOMA; CANCER; LAPAROTOMY; BIOPSY;
Keywords:
cervical carcinoma; sentinel lymph node; lymph-vascular space invasion; pelvic lymph node metastasis; paraaortic lymph node metastasis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Sakuragi, N Hokkaido0608638,ch Med, Dept Obstet & Gynecol, N 15,W 7, Sapporo, Hokkaido Hokkaido Univ N 15,W 7 Sapporo Hokkaido Japan 0608638 Hokkaido
Citazione:
N. Sakuragi et al., "Incidence and distribution pattern of pelvic and paraaortic lymph node metastasis in patients with stages IB, IIA, and IIB cervical carcinoma treatedwith radical hysterectomy", CANCER, 85(7), 1999, pp. 1547-1554

Abstract

BACKGROUND. The incidence and distribution pattern of retroperitoneal lymph node metastasis in patients with cervical carcinoma should be investigated based on data from systematic pelvic lymph node (PLN) and paraaortic lymph node (PAN) dissection, so that a basis can be established for determiningthe site of selective lymph node dissection or sampling. METHODS, A total of 208 patients with Stages IB, IIA, and IIB cervical carcinoma who underwent radical hysterectomy and systematic pelvic and PAN dissection were investigated for lymph node metastasis and histopathologic risk factors for lymph node metastasis. RESULTS, Fifty-three patients (25.5%) had lymph node metastasis. The obturator lymph nodes were most frequently involved, with a rate of 18.8% (39/208). Forty-nine of 53 node-positive patients had lymph node metastasis in the obturator, internal iliac, or common iliac lymph nodes. Of 26 solitary lymph node metastases confined to one node group, 18 were in the obturator, 3in the internal iliac, 3 in the parametrial, and 2 in the common iliac lymph nodes. A multiple logistic regression analysis revealed that deep cervical stromal invasion and lymph-vascular space invasion were related to PLN metastasis. It was also shown that metastasis to bilateral PLNs (excluding the common iliac lymph nodes) as well as metastasis to the common iliac lymph nodes were significantly related to PAN metastasis. CONCLUSIONS. The results of this study suggest that the obturator lymph nodes can be sentinel lymph nodes of cervical carcinoma. PAN metastasis appears to occur secondarily to wide-spread PLN metastasis. These results provide a basis for determining the site of selective lymph node dissection and for estimating the existence of PAN metastasis from the pattern of metastasis in PLN in patients with cervical carcinoma. (C) 1999 American Cancer Society.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/11/20 alle ore 10:50:19