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Titolo:
Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DS) as therapeutic optionsin menopause
Autore:
Katz, S; Morales, AJ;
Indirizzi:
Univ Calif San Diego, Dept Reprod Med, La Jolla, CA 92093 USA Univ Calif San Diego La Jolla CA USA 92093 od Med, La Jolla, CA 92093 USA
Titolo Testata:
SEMINARS IN REPRODUCTIVE ENDOCRINOLOGY
fascicolo: 2, volume: 16, anno: 1998,
pagine: 161 - 170
SICI:
0734-8630(1998)16:2<161:D(AD(A>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYSTEMIC LUPUS-ERYTHEMATOSUS; POSTMENOPAUSAL WOMEN; MYOCARDIAL-INFARCTION; ORAL DEHYDROEPIANDROSTERONE; PLASMA DEHYDROEPIANDROSTERONE; INSULIN-RESISTANCE; SEX-HORMONES; NORMAL MEN; CARDIOVASCULAR-DISEASE; INFLUENZA VACCINATION;
Keywords:
DHEA; aging; clinical trials; androgen replacement;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
84
Recensione:
Indirizzi per estratti:
Indirizzo: Morales, AJ EmorySAniv, Sch Med, Dept Reprod Med, 20 Linden Ave NE, Atlanta, GA 30308 U Emory Univ 20 Linden Ave NE Atlanta GA USA 30308 a, GA 30308 U
Citazione:
S. Katz e A.J. Morales, "Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DS) as therapeutic optionsin menopause", SEM REP END, 16(2), 1998, pp. 161-170

Abstract

In recent years, there has been increasing interest in the potential of androgen replacement in menopausal women and specifically adrenal androgen replacement. There is unfortunately increasing unmonitored use of dehydroepiandrosterone (DHEA) among adults in the United States with only limited and preliminary human data. An extensive body of literature in laboratory animals exists to suggest DHEA used in extremely large doses has multifaceted effects; though the inapplicability of this data to humans is not appreciated, as the physiology of adrenal androgens in humans and a few primates is unique. Currently there is much international and multidisciplinary interest in the physiology and use of DHEA "replacement" in men and menopausal women. The scientific community anxiously await the results of these investigations, but in the interim DHEA and/or DHEA-Sulfate (DHEAS) supplementation isnot recommended as a therapeutic option in menopause outside of clinical trials.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 02:56:22