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Titolo:
BIOLOGICAL BASIS OF GENERALIZED ANXIETY DISORDER
Autore:
BRAWMANMINTZER O; LYDIARD RB; RICKELS; SMALL;
Indirizzi:
MED UNIV S CAROLINA,INST PSYCHIAT,171 ASHLEY AVE CHARLESTON SC 29425
Titolo Testata:
The Journal of clinical psychiatry
, volume: 58, anno: 1997, supplemento:, 3
pagine: 16 - 26
SICI:
0160-6689(1997)58:<16:BBOGAD>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
NATIONAL-COMORBIDITY-SURVEY; PANIC DISORDER; BENZODIAZEPINE RECEPTORS; NORADRENERGIC FUNCTION; PSYCHIATRIC-DISORDERS; DIAZEPAM TREATMENT; HEALTHY-SUBJECTS; ANXIOUS PATIENTS; CHOLECYSTOKININ; RESPONSES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Citazioni:
77
Recensione:
Indirizzi per estratti:
Citazione:
O. Brawmanmintzer et al., "BIOLOGICAL BASIS OF GENERALIZED ANXIETY DISORDER", The Journal of clinical psychiatry, 58, 1997, pp. 16-26

Abstract

Despite the considerable revisions to diagnostic criteria, recent data indicate that generalized anxiety disorder (GAD) is one of the most common anxiety disorders. Growing evidence also indicates that GAD is a serious illness, which frequently causes moderate impairment and often requires prolonged treatment. Thus, investigation of the biologicalcorrelates of GAD may be helpful in the development of effective treatments for this disorder. Recent data suggest possible abnormalities in the regulatory mechanisms of several important biological componentsin GAD patients. Maladaptive responses to stressful stimuli have beenobserved in the locus-ceruleus-norepinephrine-sympathetic nervous system, the hypothalamic-pituitary-adrenocortical axis, and the cholecystotin system. Abnormalities in other important CNS modulators, such as 5-HT and gamma-aminobutyric acid, may also be involved in the biology of GAD. In the following article, the authors will review the existinginformation regarding these potential biological abnormalities in GAD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 21:37:20