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Titolo:
Predictors of skeletal muscle mass in elderly men and women
Autore:
Baumgartner, RN; Waters, DL; Gallagher, D; Morley, JE; Garry, PJ;
Indirizzi:
Vet Adm Med Ctr, Ctr Geriatr Res Educ & Clin, St Louis, MO 63104 USA Vet Adm Med Ctr St Louis MO USA 63104 Educ & Clin, St Louis, MO 63104 USA Univ New Mexico, Sch Med, Clin Nutr Program, Albuquerque, NM USA Univ New Mexico Albuquerque NM USA lin Nutr Program, Albuquerque, NM USA ColumbiaYUniv, St Lukes Roosevelt Hosp, Dept Med, Obes Res Ctr, New York, N Columbia Univ New York NY USA Hosp, Dept Med, Obes Res Ctr, New York, N St Louis Univ, Hlth Sci Ctr, Div Geriatr Med, St Louis, MO 63104 USA St Louis Univ St Louis MO USA 63104 v Geriatr Med, St Louis, MO 63104 USA
Titolo Testata:
MECHANISMS OF AGEING AND DEVELOPMENT
fascicolo: 2, volume: 107, anno: 1999,
pagine: 123 - 136
SICI:
0047-6374(19990301)107:2<123:POSMMI>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
X-RAY ABSORPTIOMETRY; GROWTH FACTOR-I; BODY-COMPOSITION; OLDER MEN; PHYSICAL-ACTIVITY; AGE; HORMONE; SARCOPENIA; POPULATION;
Keywords:
predictors; skeletal muscle mass; elderly men; elderly women;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Morley, JE VetStdm Med Ctr, Ctr Geriatr Res Educ & Clin, 1402 S Grand Blvd,Room M238, Vet Adm Med Ctr 1402 S Grand Blvd,Room M238 St Louis MO USA 63104
Citazione:
R.N. Baumgartner et al., "Predictors of skeletal muscle mass in elderly men and women", MECH AGE D, 107(2), 1999, pp. 123-136

Abstract

Background: Elderly men and women lose muscle mass and strength with increasing age. Decreased physical activity, hormones, malnutrition and chronic disease have been identified as factors contributing to this loss. There are few data, however, for their multivariate associations with muscle mass and strength. This study analyzes these associations in a cross-sectional sample of elderly people from the New Mexico Aging Process Study. Methods: Data collected in 1994 for 121 male and 180 female volunteers aged 65-97 years of age enrolled in The New Mexico Aging Process Study were analyzed. Bodycomposition was measured using dual energy X-ray absorptiometry; dietary intake from 3 day food records: usual physical activity by questionnaire; health status from annual physical examinations; and serum testosterone? estrone, sex-hormone binding globulin (SHBG), and insulin-like growth factor (IGF1) from radioimmunoassays of fasting blood samples. Statistical analyses included partial correlation and stepwise multiple regression. Results: Themuscle mass and strength (adjusted for knee height) decreased with increasing age in both sexes. The muscle mass was significantly associated with serum free-testosterone; physical activity, cardiovascular disease, and IGF1 in the men. In the women, the muscle mass was significantly associated withtotal fat mass and physical activity. Age was not associated significantlywith muscle mass after controlling for these variables. Grip strength was associated with age independent of muscle mass in both sexes. Estrogen (endogenous and exogenous) was not associated with muscle mass or strength in women. Conclusions: Age-related loss of muscle mass and strength occurs in relatively healthy, well-nourished elderly men and women and has a multifactorial basis. Sex hormone status is an important factor in men but not in women. Physical activity is an important predictor of muscle mass in both sexes. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 09:57:24