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Titolo:
Effects of nitinol Strecker stent placement on vascular response in normaland stenotic porcine iliac arteries
Autore:
Froelich, JJ; Alfke, H; Wilke, A; Ramaswamy, A; Barth, KH; Hoppe, M; Wagner, HJ; Klose, KJ;
Indirizzi:
Philipps Univ Hosp, Dept Radiol, D-35043 Marburg, Germany Philipps Univ Hosp Marburg Germany D-35043 iol, D-35043 Marburg, Germany Philipps Univ Hosp, Dept Orthoped Surg, D-35043 Marburg, Germany Philipps Univ Hosp Marburg Germany D-35043 urg, D-35043 Marburg, Germany Philipps Univ Hosp, Dept Pathol, D-35043 Marburg, Germany Philipps Univ Hosp Marburg Germany D-35043 hol, D-35043 Marburg, Germany Georgetown Univ Hosp, Div Vasc & Intervent Radiol, Washington, DC 20007 USA Georgetown Univ Hosp Washington DC USA 20007 ol, Washington, DC 20007 USA
Titolo Testata:
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
fascicolo: 3, volume: 10, anno: 1999,
pagine: 329 - 338
SICI:
1051-0443(199903)10:3<329:EONSSP>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXPANDING METALLIC STENTS; FEMORAL ARTERIES; TANTALUM STENTS; SMALL VESSELS; PROGRESS; WORK; ATHEROSCLEROSIS; ENDOPROSTHESES; ANGIOGRAPHY; HYPERPLASIA;
Keywords:
arteries, iliac; arteries, stenosis or obstruction; stents and prostheses;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Froelich, JJ Philipps Univ Hosp, Dept Radiol, Baldingerstr, D-35043 Marburg, Germany Philipps Univ Hosp Baldingerstr Marburg Germany D-35043 many
Citazione:
J.J. Froelich et al., "Effects of nitinol Strecker stent placement on vascular response in normaland stenotic porcine iliac arteries", J VAS INT R, 10(3), 1999, pp. 329-338

Abstract

PURPOSE: This experimental study was conducted to evaluate neointimal thickness, lumen diameters, and histologic changes in normal and stenotic porcine iliac arteries following placement of self-expanding nitinol Strecker stents,MATERIALS AND METHODS: Neointimal trauma causing slight vascular stenosis was induced unilaterally within external iliac arteries of 12 swines by means of endothelial abrasion and high cholesterol diet. Nitinol Strecker stents were placed within the stenotic and the normal contralateral vascular segments. For histopathologic evaluation, the pigs were killed 12 or 24 weeksafter stent placement and luminal diamters were evaluated angiographically,RESULTS: Excluding one occlusion, 15% narrowing of the lumen diameter was induced unilaterally (P = .002), Initial luminal gain after stent placementwas greater for stenotic than for normal arteries. The amount of neointimathickness was not different between stenotic and normal vessels (P > .05),Comparing vascular diameters before stent placement and at follow-up, luminal loss due to neointima proliferation was 22% within normal arteries (P =.0002), while a luminal gain by 15% was found within the stenotic arteries(P = .008), Maturation of neointima and endothelial coverage were completeafter 24 weeks. CONCLUSIONS: Even though nitinol Strecker stents induce excessive neointimal proliferation, stenotic arteries seem to profit from great early luminalgain resulting in 15% of vascular expansion at follow-up while slight stenosis is induced within normal iliac arteries.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 01:19:20