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Titolo:
Study and modulation of human cortical excitability with transcranial magnetic stimulation
Autore:
Pascual-Leone, A; Tormos, JM; Keenan, J; Tarazona, F; Canete, C; Catala, MD;
Indirizzi:
HarvardDept Sch, Beth Israel Deaconess Med Ctr, Lab Magnet Brain Stimulat,Harvard Med Sch Boston MA USA 01778 s Med Ctr, Lab Magnet Brain Stimulat, Univ Valencia, Dept Fisiol, Valencia, Spain Univ Valencia Valencia Spain niv Valencia, Dept Fisiol, Valencia, Spain Consejo Super Invest Cient, Inst Cajal, Valencia, Spain Consejo Super Invest Cient Valencia Spain , Inst Cajal, Valencia, Spain
Titolo Testata:
JOURNAL OF CLINICAL NEUROPHYSIOLOGY
fascicolo: 4, volume: 15, anno: 1998,
pagine: 333 - 343
SICI:
0736-0258(199807)15:4<333:SAMOHC>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN MOTOR CORTEX; AMYOTROPHIC-LATERAL-SCLEROSIS; SILENT PERIOD; PARKINSONS-DISEASE; VOLUNTARY CONTRACTION; BRAIN-STIMULATION; MAJOR DEPRESSION; MUSCLE RESPONSES; CEREBRAL-CORTEX; INHIBITION;
Keywords:
repetitive transcranial magnetic stimulation; neuroimaging; cortical excitability;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
68
Recensione:
Indirizzi per estratti:
Indirizzo: Pascual-Leone, A HarvardDept Sch, Beth Israel Deaconess Med Ctr, Lab Magnet Brain Stimulat, Harvard Med Sch 330 Brookline Ave Boston MA USA 01778 at,
Citazione:
A. Pascual-Leone et al., "Study and modulation of human cortical excitability with transcranial magnetic stimulation", J CL NEURPH, 15(4), 1998, pp. 333-343

Abstract

Transcranial magnetic stimulation (TMS) can be applied in different paradigms to obtain a measure of various aspects of cortical excitability. These different TMS paradigms provide information about different neurotransmitter systems, enhance our understanding about the pathophysiology of neuropsychiatric conditions, and in the future may be helpful as a guide for pharmacological interventions. In addition, repetitive TMS (rTMS) modulates cortical excitability beyond the duration of the rTMS trains themselves. Depending on rTMS parameters, a lasting inhibition or facilitation of cortical excitability can be induced. These effects can be demonstrated neurophysiologically or by combining rTMS with neuroimaging techniques. The effects do not remain limited to the cortical area directly targeted by rTMS, but affect awider neural network transynaptically. Modulation of cortical excitabilityby rTMS may in the future be useful not only as a research tool but also as a therapeutic intervention in neurology, psychiatry, and neurorehabilitation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 15:03:55