Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Origins of the glycinergic inputs to the rat locus coeruleus and dorsal raphe nuclei: a study combining retrograde tracing with glycine immunohistochemistry
Autore:
Rampon, C; Peyron, C; Gervasoni, D; Pow, DV; Luppi, PH; Fort, P;
Indirizzi:
INSERM, U480, F-69008 Lyon, France INSERM Lyon France F-69008INSERM, U480, F-69008 Lyon, France Univ Queensland, Vis Touch & Hearing Res Ctr, Brisbane, Qld, Australia Univ Queensland Brisbane Qld Australia Res Ctr, Brisbane, Qld, Australia
Titolo Testata:
EUROPEAN JOURNAL OF NEUROSCIENCE
fascicolo: 3, volume: 11, anno: 1999,
pagine: 1058 - 1066
SICI:
0953-816X(199903)11:3<1058:OOTGIT>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
SUPERIOR OLIVARY COMPLEX; SLEEP-WAKING CYCLE; LOWER BRAIN-STEM; TOXIN-B SUBUNIT; PERIAQUEDUCTAL GRAY; IMMUNOREACTIVE NEURONS; COCHLEAR NUCLEUS; IONTOPHORETIC APPLICATION; SPINAL MOTONEURONS; PARADOXICAL SLEEP;
Keywords:
amino acid; inhibitory neurotransmitter; monoamine; noradrenaline; paradoxical sleep; serotonin;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
60
Recensione:
Indirizzi per estratti:
Indirizzo: Luppi, PH INSERM, U480, F-69008 Lyon, France INSERM Lyon France F-69008INSERM, U480, F-69008 Lyon, France
Citazione:
C. Rampon et al., "Origins of the glycinergic inputs to the rat locus coeruleus and dorsal raphe nuclei: a study combining retrograde tracing with glycine immunohistochemistry", EUR J NEURO, 11(3), 1999, pp. 1058-1066

Abstract

The amino acid glycine is a major inhibitory neurotransmitter in the brainstem and is likely involved in the tonic inhibition of the monoaminergic neurons during all sleep-waking stages. In order to determine the neurons at the origin of the glycinergic innervation of the two principal monoaminergic nuclei, the locus coeruleus and the dorsal raphe of the rat, we applied adouble-labelling technique, combining retrograde transport of cholera-toxin B subunit with glycine immunohistochemistry. Using this technique, we found that the locus coeruleus and dorsal raphe nuclei receive a common glycinergic innervation from the ventral and ventrolateral periaqueductal grey, including the adjacent deep mesencephalic reticular nucleus. Small additional glycinergic inputs to these nuclei originated from the lateral paragigantocellular nucleus and the rostral ventromedial medullary reticular formation. The potential role of these glycinergic inputs in the control of the excitability of the monoaminergic neurons of the locus coeruleus and dorsal raphe nuclei is discussed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 01:36:53