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Titolo:
PROGNOSTIC-SIGNIFICANCE OF SYSTOLIC BLOOD-PRESSURE CHANGES DURING DOBUTAMINE-ATROPINE STRESS TC-99M SESTAMIBI PERFUSION SCINTIGRAPHY IN PATIENTS WITH CHEST PAIN AND KNOWN OR SUSPECTED CORONARY-ARTERY DISEASE
Autore:
GELEIJNSE ML; ELHENDY A; VANDOMBURG RT; RAMBALDI R; REIJS AEM; ROELANDT JRTC; FIORETTI PM;
Indirizzi:
UNIV HOSP DIJKZIGT,THORAXCTR,BA 302,DR MOLEWATERPLEIN 40 NL-3015 GD ROTTERDAM NETHERLANDS UNIV HOSP DIJKZIGT,DEPT NUCL MED NL-3015 GD ROTTERDAM NETHERLANDS ERASMUS UNIV ROTTERDAM ROTTERDAM NETHERLANDS
Titolo Testata:
The American journal of cardiology
fascicolo: 8, volume: 79, anno: 1997,
pagine: 1031 - 1035
SICI:
0002-9149(1997)79:8<1031:POSBCD>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
DYNAMIC INTRAVENTRICULAR OBSTRUCTION; MYOCARDIAL-INFARCTION; ECHOCARDIOGRAPHY; HYPOTENSION; EXERCISE; TOMOGRAPHY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
M.L. Geleijnse et al., "PROGNOSTIC-SIGNIFICANCE OF SYSTOLIC BLOOD-PRESSURE CHANGES DURING DOBUTAMINE-ATROPINE STRESS TC-99M SESTAMIBI PERFUSION SCINTIGRAPHY IN PATIENTS WITH CHEST PAIN AND KNOWN OR SUSPECTED CORONARY-ARTERY DISEASE", The American journal of cardiology, 79(8), 1997, pp. 1031-1035

Abstract

To investigate the prognostic value of dobutamine stress-induced changes in systolic blood pressure (BP) 418 patients (mean age 60 years, 238 men) with chest pain and known or suspected coronary artery disease, who underwent a dobutamine-atropine stress technetium-99m sestamibi myocardial perfusion scintigraphic study, were followed up for 25 +/- 15 months. Blood pressure was measured by automatic sphygmomanometry every 3 minutes. A marked decrease and increase In systolic BP from rest to peak were defined as changes of greater than or equal to 20 mm Hg, and greater than or equal to 30 mm Hg, respectively. Worst outcome events were cardiac death (n = 30), nonfatal myocardial infarction (n =17), and hospitalization for congestive heart failure (n = 8) A decrease in systolic BP (prevalence 16%) was associated with older age and higher baseline systolic BP. Fixed and reversible sestamibi perfusion defects and follow-up results were similar to patients without a systolic BP decrease. In contrast, an increase in systolic BP (prevalence 24%) wets associated with younger age, lower baseline systolic BP, and with absence of a history of prior congestive heart failure or treatment with angiotensin-converting enzyme inhibitors. Furthermore, these patients had fewer fixed perfusion defects and tended to have fewer annual event rates (3.5% vs 7.5%, p < 0.10). In a multivariate model, an increase In systolic BP was not on independent predictor for subsequent events. In conclusion, a dobutamine-induced decrease in Systolic BP is not associated with fixed or reversible sestamibi defects or adverse prognosis. An increase In systolic BP, however, is associated with less fixed sestamibi defects and a tendency toward less annual event rates. (C) 1997 by Excerpta Medico, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/20 alle ore 01:05:26