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Titolo:
Fine needle aspiration diagnosis of mycobacterial lymphadenitis - Sensitivity and predictive value in the United States
Autore:
Ellison, E; Lapuerta, P; Martin, SE;
Indirizzi:
Univ So Calif, Dept Pathol, Los Angeles, CA 90033 USA Univ So Calif Los Angeles CA USA 90033 Pathol, Los Angeles, CA 90033 USA Univ So Calif, Dept Med, Los Angeles, CA 90033 USA Univ So Calif Los Angeles CA USA 90033 ept Med, Los Angeles, CA 90033 USA
Titolo Testata:
ACTA CYTOLOGICA
fascicolo: 2, volume: 43, anno: 1999,
pagine: 153 - 157
SICI:
0001-5547(199903/04)43:2<153:FNADOM>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
TUBERCULOUS CERVICAL LYMPHADENOPATHY; CYTOLOGY DIAGNOSIS; BIOPSY; CYTODIAGNOSIS;
Keywords:
lymphadenitis; Mycobacterium; aspiration biopsy; HIV; granuloma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Martin, SE Univ So Calif, Dept Pathol, NOR 2420,Hlth Sci Campus, Los Angeles, CA 90033 Univ So Calif NOR 2420,Hlth Sci Campus Los Angeles CA USA 90033
Citazione:
E. Ellison et al., "Fine needle aspiration diagnosis of mycobacterial lymphadenitis - Sensitivity and predictive value in the United States", ACT CYTOL, 43(2), 1999, pp. 153-157

Abstract

OBJECTIVE: Fine needle aspiration (FNA) has proven valuable in diagnosing tuberculous lymphadenitis in countries with endemic mycobacterial infection(MI). Its role in developed countries, where sensitivity and positive predictive value are likely to be lower, has not been adequately explored. STUDY DESIGN: This retrospective, five-year study from a public hospital in the United States examined the predictiveness of 238 nodal FNAs in patients with MI; 59% of patients were also HIV+. RESULTS: Diagnostic results (stainable acid-fast bacilli or positive culture) were present in nearly half the aspirates; sensitivity was 46%, specificity 100%, positive predictive value (PPV) 100% and negative predictive value (NPV) 94%. If granulomatous inflammation (GI) was also considered a positive result, sensitivity increased to 53%; false positive cases of GI reduced PPV to 80%, while specificity (98%) and NPV (95%) changed little. Considered alone, GI had the lowest sensitivity (25%) and PPV (65%). CONCLUSION: FNA was useful in this U.S. population with MI, identifying almost half the affected patients. However, nondiagnostic results, such asa granulomatous inflammation, should be interpreted with caution.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 00:28:48