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Titolo:
Abnormal increase in the corticomotor output to the affected hand during repetitive transcranial magnetic stimulation of the primary motor cortex in patients with writer's cramp
Autore:
Siebner, HR; Auer, C; Conrad, B;
Indirizzi:
Tech Univ Munich, Dept Neurol, D-81675 Munich, Germany Tech Univ Munich Munich Germany D-81675 Neurol, D-81675 Munich, Germany
Titolo Testata:
NEUROSCIENCE LETTERS
fascicolo: 2, volume: 262, anno: 1999,
pagine: 133 - 136
SICI:
0304-3940(19990305)262:2<133:AIITCO>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
INHIBITION; EXCITABILITY; DYSTONIA; RESPONSES;
Keywords:
focal task-specific dystonia; human motor cortex; repetitive transcranial magnetic stimulation; cortical excitability; intracortical inhibition; writer's cramp;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Siebner, HR Tech Univ Munich, Dept Neurol, Moehlstr 28, D-81675 Munich, Germany Tech Univ Munich Moehlstr 28 Munich Germany D-81675 , Germany
Citazione:
H.R. Siebner et al., "Abnormal increase in the corticomotor output to the affected hand during repetitive transcranial magnetic stimulation of the primary motor cortex in patients with writer's cramp", NEUROSCI L, 262(2), 1999, pp. 133-136

Abstract

In fourteen right-handed patients with writer's cramp and 10 right-handed controls, 10 trains of suprathreshold 1 Hz repetitive transcranial magneticstimulation (rTMS) were applied over the left primary motor hand area. Each rTMS train lasted for a minute with an intertrain interval of 10 s. The motor evoked potentials (MEPs) were recorded from the relaxed contralateral first dorsal interosseus muscle. The mean MEP area of each rTMS train was taken as a measure of the corticospinal motor output to the affected hand. While the mean MEP area decreased significantly in controls, patients showeda significant increase in mean MEP area during rTMS. The differential effect on MEP size was highly significant. The abnormal rTMS-associated facilitation of the corticomotor output to the affected hand demonstrates an increased excitability of the corticospinal motor system in writer's cramp. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 19:40:00