Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
VITAMIN-D LEVELS IN CHILDREN WITH CYSTIC-FIBROSIS
Autore:
HENDERSON RC; LESTER G;
Indirizzi:
237 BURNETT WOMACK BLDG,CB 7055 CHAPEL HILL NC 27599 UNIV N CAROLINA,DEPT PEDIAT CHAPEL HILL NC 00000 UNIV N CAROLINA,DEPT ORTHOPAED CHAPEL HILL NC 00000 UNIV N CAROLINA,DEPT PHARMACOL CHAPEL HILL NC 00000
Titolo Testata:
Southern medical journal
fascicolo: 4, volume: 90, anno: 1997,
pagine: 378 - 383
SICI:
0038-4348(1997)90:4<378:VLICWC>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
BONE-MINERAL DENSITY; SERUM 1,25-DIHYDROXYVITAMIN-D; 25-HYDROXYVITAMIN-D; ADULTS; CHILDHOOD; ASSAY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
35
Recensione:
Indirizzi per estratti:
Citazione:
R.C. Henderson e G. Lester, "VITAMIN-D LEVELS IN CHILDREN WITH CYSTIC-FIBROSIS", Southern medical journal, 90(4), 1997, pp. 378-383

Abstract

Serum levels of the important hormone 1,25-dihydroxyvitamin D (1,25-diOHD, calcitriol) have not been extensively evaluated in patients withcystic fibrosis (CF) during the critical period of skeletal growth and development. This study was a cross-sectional, observational assessment of 25-hydroxyvitamin D (25-OHD, calcidiol) and 1,25-diOHD levels in 54 patients with CF. The patients' ages ranged from 4.9 years to 19.5 years (mean, 11.0 years). Levels were correlated with pulmonary function tests, chest x-ray scores, height and weight Z scores, skinfold percentiles, CF genotype, serum chemistries, and use of a vitamin supplement. Levels were compared with those in more than 160 other pediatric patients living in the same region, and all assays were done in the same laboratory. Despite low-normal levels of the 25-OHD precursor, there was a high prevalence of low (18%) and marginal (18%) levels of 1,25-diOHD. None of the various parameters examined correlated with either 25-OHD or 1,25-diOHD levels. The cause, clinical significance, and treatment of low levels of this important hormone in children with CF warrant further study.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 17:22:10