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Titolo:
Eosinophilic pustulosis and immune deficit in childhood.
Autore:
Rybojad, M; Guibal, F; Vignon-Pennamen, MD; Prigent, F; Morel, P; Bourrat, E;
Indirizzi:
Hop St Louis, Serv Dermatol, F-75475 Paris, France Hop St Louis Paris France F-75475 , Serv Dermatol, F-75475 Paris, France
Titolo Testata:
ANNALES DE DERMATOLOGIE ET DE VENEREOLOGIE
fascicolo: 1, volume: 126, anno: 1999,
pagine: 29 - 31
SICI:
0151-9638(199901)126:1<29:EPAIDI>2.0.ZU;2-5
Fonte:
ISI
Lingua:
FRE
Soggetto:
FOLLICULITIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Bourrat, E Hopnce Louis, Policlin Dermatol, 1 Ave Claude Vellefaux, F-75010 Paris, Fra Hop St Louis 1 Ave Claude Vellefaux Paris France F-75010 , Fra
Citazione:
M. Rybojad et al., "Eosinophilic pustulosis and immune deficit in childhood.", ANN DER VEN, 126(1), 1999, pp. 29-31

Abstract

Background. Eosinophilic is a skin eruption which occurs in the first years of life, progressing by pruriginous flare-ups with amicrobial papulopustulae on a hairless scalp. Eosinophil infiltration of the skin is variable (follicular or perifollicular dermal infiltration). In adults, eosinophilic pustulosis is often associated with immune deficiency, but this association has not been reported in children. We report two cases. Case reports. Two boys had a pruriginous papulopustular eruption involvingthe scalp and the trunk which had progressed with periods of exacerbation since birth. Search for bacteriological or mycological involvement was negative. Histology showed folliculitis with major polynuclear eosinophil infiltration. Both children had a past history of repeated skin and extracutaneous infections strongly suggesting an immune deficit. Buckly syndrome was suspected in the second case. Discussion. Juvenile eosinophilic pustulosis belongs to the spectrum of childhood eosinophilic dermatoses. The presence of eosinophil infiltration inthe skin demonstrates localized or systemic immune dysfunction. A hematology and immunology work-up is needed in case of associated skin or deep infections.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/07/20 alle ore 08:09:34