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Titolo:
Homeostasis of taurine and glutamate plasma levels after acute and chronicethanol administration in man
Autore:
Ward, RJ; Marshall, EJ; Ball, D; Martinez, J; De Witte, P;
Indirizzi:
Univ Catholique Louvain, B-1348 Louvain, Belgium Univ Catholique Louvain Louvain Belgium B-1348 , B-1348 Louvain, Belgium Inst Psychiat, Addict Sci Ctr, London, England Inst Psychiat London England Psychiat, Addict Sci Ctr, London, England
Titolo Testata:
NEUROSCIENCE RESEARCH COMMUNICATIONS
fascicolo: 1, volume: 24, anno: 1999,
pagine: 41 - 49
SICI:
0893-6609(199901/02)24:1<41:HOTAGP>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALCOHOL DEPENDENCE; NUCLEUS-ACCUMBENS; AMINO-ACIDS; RAT-BRAIN; TRANSPORTER; WITHDRAWAL; QUESTIONNAIRE; RELIABILITY; INCREASES; VALIDITY;
Keywords:
taurine; alcohol abusers; alcohol detoxification; glutamic acid; amino acids;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Ward, RJ Univ Catholique Louvain, B-1348 Louvain, Belgium Univ Catholique Louvain Louvain Belgium B-1348 Louvain, Belgium
Citazione:
R.J. Ward et al., "Homeostasis of taurine and glutamate plasma levels after acute and chronicethanol administration in man", NEUROSC R C, 24(1), 1999, pp. 41-49

Abstract

Taurine homeostasis is perturbed after acute and chronic ethanol administration. An oral dose of ethanol, (0.8 g / kg) significantly decreased the plasma taurine content 90 minutes after its administration, while glutamic acid content increased significantly at 30 minutes. Chronic alcohol abusers, showed significant increases in plasma taurine content 7 days after alcoholwithdrawal. In 50% of these patients the taurine levels exceeding the reference range and correlated with the elevated levels of plasma glutamic acid. In addition in these patients there was also a significant decrease in anxiety score, CIWA Ar, (p<0.01). Although the correlation between taurine and glutamate has been described in other diseases this is the first time that such changes have been reported after acute or chronic ethanol administration.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 06:15:14