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Titolo:
Chronic neuropsychological sequelae in a case of severe lithium intoxication
Autore:
Brumm, VL; van Gorp, WG; Wirshing, W;
Indirizzi:
Univ,So Calif, Childrens Hosp Los Angeles, Sch Med, Div Neurol, Los Angeles Univ So Calif Los Angeles CA USA 90027 , Sch Med, Div Neurol, Los Angeles Dept Vet Affairs Med Ctr, Psychiat Serv, Los Angeles, CA USA Dept Vet Affairs Med Ctr Los Angeles CA USA at Serv, Los Angeles, CA USA Univ Calif Los Angeles, Sch Med, Dept Psychiat & Biobehav Sci, Los Angeles, Univ Calif Los Angeles Los Angeles CA USA 90024 iobehav Sci, Los Angeles, Cornell Univ, Coll Med, Dept Psychiat, New York, NY USA Cornell Univ New York NY USA , Coll Med, Dept Psychiat, New York, NY USA
Titolo Testata:
NEUROPSYCHIATRY NEUROPSYCHOLOGY AND BEHAVIORAL NEUROLOGY
fascicolo: 4, volume: 11, anno: 1998,
pagine: 245 - 249
SICI:
0894-878X(199810)11:4<245:CNSIAC>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERMANENT NEUROLOGICAL DEFICITS; TOXICITY; NEUROTOXICITY; MEMORY; CARBONATE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Brumm, VL Univ So Calif, Childrens Hosp Los Angeles, Sch Med, Div Neurol, 4650 Sunset Univ So Calif 4650 Sunset Blvd,Mailstop 82 Los Angeles CA USA 90027
Citazione:
V.L. Brumm et al., "Chronic neuropsychological sequelae in a case of severe lithium intoxication", NEUROPS NEU, 11(4), 1998, pp. 245-249

Abstract

Objective: This case provides data from serial assessments using a comprehensive neuropsychological test battery to assess the effects of severe toxicity on cognitive functioning, the pattern of deficits, and the regions of the brain that appear to be involved. Background: Lithium carbonate has made a significant contribution to the treatment of bipolar disorder, and considerable investigation has been conducted on both temporary and long-term side effects an the central nervous system. The effects of acute lithium intoxication on the central nervous system have been extensively documented. Method: We studied a severe case of acute lithium intoxication and associated neuropsychological sequelae. The patient was evaluated twice with a comprehensive battery of neuropsychological tests within 2 years of the Lithium intoxication. Results: Comprehensive neuropsychological evaluations indicated persistent cognitive sequelae, including impaired memory, attention, executive control functions, and visuospatial deficits. Conclusions: The cognitive sequelae noted in the case of lithium toxicity are consistent with a subcortical dementia and the findings of other authors. Findings should be explored further in more rigorous clinical studies.

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Documento generato il 02/04/20 alle ore 19:05:45