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Titolo:
Automatic three-dimensional multimodality registration using radionuclide transmission CT attenuation maps: A phantom study
Autore:
Dey, D; Slomka, PJ; Hahn, LJ; Kloiber, R;
Indirizzi:
Univ5,estern Ontario, London Hlth Sci Ctr, Dept Nucl Med, London, ON N6A 4G Univ Western Ontario London ON Canada N6A 4G5 Nucl Med, London, ON N6A 4G Univ Calgary, Dept Phys & Astron, Calgary, AB T2N 1N4, Canada Univ Calgary Calgary AB Canada T2N 1N4 stron, Calgary, AB T2N 1N4, Canada Univ Calgary, Dept Radiol, Calgary, AB T2N 1N4, Canada Univ Calgary Calgary AB Canada T2N 1N4 adiol, Calgary, AB T2N 1N4, Canada Foothills Hosp, Div Nucl Med, Calgary, AB T2N 2T9, Canada Foothills Hosp Calgary AB Canada T2N 2T9 Med, Calgary, AB T2N 2T9, Canada
Titolo Testata:
JOURNAL OF NUCLEAR MEDICINE
fascicolo: 3, volume: 40, anno: 1999,
pagine: 448 - 455
SICI:
0161-5505(199903)40:3<448:ATMRUR>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMAGE REGISTRATION; 3-DIMENSIONAL REGISTRATION; SPECT; COMPENSATION; PET; QUANTIFICATION; ALGORITHM; SCANS; BRAIN;
Keywords:
coregistration; automated image registration; transmission attenuation maps;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Slomka, PJ Univriastern Ontario, London Hlth Sci Ctr, Dept Nucl Med, 75 South St,Victo Univ Western Ontario 75 South St,Victoria Campus London ON Canada N6A 4G5
Citazione:
D. Dey et al., "Automatic three-dimensional multimodality registration using radionuclide transmission CT attenuation maps: A phantom study", J NUCL MED, 40(3), 1999, pp. 448-455

Abstract

Coregistration of images from a single subject, acquired by different modalities, is important in clinical diagnosis, surgery and therapy planning. The purpose of this study was to evaluate, using a physical torso phantom, anovel, fully automated method for three-dimensional image registration of CT and SPECT, using radionuclide transmission (RNT) attenuation maps. Methods: We obtained CT scans and SPECT scans paired with RNT maps of an anthropomorphic cardiac phantom, RNT attenuation maps were acquired using an uncollimated Tc-99m-filled flood source. RNT and SPECT scans were acquired in the same spatial orientation (usual clinical practice in nonuniform attenuation correction). In addition, CT attenuation maps (CTMAPs) for Tc-99m SPECT were generated from CT by linear energy scaling. RNT maps were registered to CT and CTMAPs by iterative simplex minimization of count difference and uniformity index (sum of RNT map intensity variances corresponding to each intensity level in the CT volume). In each iteration, three shifts and threeangles were adjusted. To register SPECT to CT, we applied the RNT transformation parameters to SPECT. Results: RNT maps could be registered to CT andCTMAP images using both criteria. The average three-dimensional distance between landmark and automated registration was 2.5 +/- 1.2 mm for count difference and 3.3 +/- 1.3 mm for uniformity index. The three-dimensional reproducibility errors were 1.2 +/- 0.7 mm for count difference, 2.1 +/- 0.5 mmfor uniformity index and 2.3 +/- 1.0 mm for manual marker registration. The minimization of uniformity index was robust when up to 50% CT or RNT slices were missing and was not affected significantly (<2 mm) by realistic variation in CT values (+/-12 Hounsfield units). Conclusion: In addition to typical use in nonuniform attenuation correction, RNT maps can be used for fully automated three-dimensional registration of SPECT to CT. Such registration is not affected by features and quality of SPECT images and avoids difficulties associated with fiducial markers. Our method can be applied to SPECT-CT registration of various organs, such as brain, heart, lungs, breasts and abdomen, including oncological scans.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 15:48:20