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Titolo:
The controversial M cell
Autore:
Anyukhovsky, EP; Sosunov, EA; Gainullin, RZ; Rosen, MR;
Indirizzi:
Columbia Univ Coll Phys & Surg, Dept Pharmacol, New York, NY 10032 USA Columbia Univ Coll Phys & Surg New York NY USA 10032 w York, NY 10032 USA Columbia Univ Coll Phys & Surg, Dept Pediat, New York, NY 10032 USA Columbia Univ Coll Phys & Surg New York NY USA 10032 w York, NY 10032 USA Inst Expt Cardiol, Lab Heart Electrophysiol, Moscow, Russia Inst Expt Cardiol Moscow Russia ab Heart Electrophysiol, Moscow, Russia Inst Cell Biophys, Lab Med Biophys, Pushchino, Russia Inst Cell Biophys Pushchino Russia , Lab Med Biophys, Pushchino, Russia
Titolo Testata:
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
fascicolo: 2, volume: 10, anno: 1999,
pagine: 244 - 260
SICI:
1045-3873(199902)10:2<244:TCMC>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSIENT OUTWARD CURRENT; CANINE VENTRICULAR EPICARDIUM; SODIUM-CHANNEL BLOCK; TORSADE-DE-POINTES; LONG-QT SYNDROME; ACTIVATION-RECOVERY INTERVALS; MONOPHASIC ACTION-POTENTIALS; TRIGGERED ACTIVITY; ELECTROPHYSIOLOGICAL PROPERTIES; PURKINJE-FIBERS;
Keywords:
cardiac electrophysiology; ventricular action potentials; ventricular electrograms; transmural gradients; activation-recovery intervals;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
101
Recensione:
Indirizzi per estratti:
Indirizzo: Rosen, MR Columbiaewniv Coll Phys & Surg, Dept Pharmacol, 630 W 168th St,PH7 W-321, N Columbia Univ Coll Phys & Surg 630 W 168th St,PH7 W-321 New York NY USA 10032
Citazione:
E.P. Anyukhovsky et al., "The controversial M cell", J CARD ELEC, 10(2), 1999, pp. 244-260

Abstract

The Controversial M Cell. A recent publication by us has been interpreted by some as arguing against the existence and importance of M cells. We suppose this is the reason we have been asked to write this "controversy. " Regrettably for the controversy, neither our work nor we deny the existence of M cells. Rather, we have confirmed, conceivably ad nauseum, that M cells doexist and contribute importantly to the expression of electrical activity in the intact myocardium. What controversy there is relates to (1) whether there is an inhomogeneous transmural gradient for ventricular repolarization in normal hearts, and (2) why the electrophysiologic properties of different myocardial sites differ so markedly at the level of the isolated tissueand single cell and yet become so much more homogenous in the intact ventricle, These issues are addressed on the following pages.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 04:47:12