Catalogo Articoli (Spogli Riviste)

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Titolo:
Comparative experimental study of esophageal wall regeneration after prosthetic replacement
Autore:
Freud, E; Efrati, I; Kidron, D; Finally, R; Mares, AJ;
Indirizzi:
Tel78viv Univ, Schneider Childrens Med Ctr Israel, Dept Pediat Surg, IL-699 Tel Aviv Univ Tel Aviv Israel IL-69978 Israel, Dept Pediat Surg, IL-699 Bena,urion Univ Negev, Soroka Med Ctr, Dept Pediat Surg, IL-84105 Beer Shev Ben Gurion Univ Negev Beer Sheva Israel IL-84105 urg, IL-84105 Beer Shev TellAviv Univ, Schneider Childrens Med Ctr Israel, Dept Pathol, IL-69978 Te Tel Aviv Univ Tel Aviv Israel IL-69978 Israel, Dept Pathol, IL-69978 Te
Titolo Testata:
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH
fascicolo: 2, volume: 45, anno: 1999,
pagine: 84 - 91
SICI:
0021-9304(199905)45:2<84:CESOEW>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Keywords:
esophageal reconstruction; esophageal prosthesis; polytetrafluoroethylene; Dacron; Lyodura;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Freud, E Tel78viv Univ, Schneider Childrens Med Ctr Israel, Dept Pediat Surg, IL-699 Tel Aviv Univ Tel Aviv Israel IL-69978 Dept Pediat Surg, IL-699
Citazione:
E. Freud et al., "Comparative experimental study of esophageal wall regeneration after prosthetic replacement", J BIOMED MR, 45(2), 1999, pp. 84-91

Abstract

This study compares three prosthetic materials for potential use in patching and bridging congenital and acquired esophageal defects. The study was divided into two parts. in the first part, fulll-thickness, 6-cm(2) cervicalesophageal defects were induced in three groups of young mongrel dogs and were replaced with patches of lyophilized dura mater (Lyodura), polyethylene terephthalate (Dacron), or expanded polytetrafluoroethylene (PTFE). The dogs in the Lyodura subgroup were scheduled to be sacrificed after 1, 2, 4, 8, and 12 weeks and the dogs in the PTFE and Dacron subgroups were sacrificed after 1, 2, 3, 4, 6, and 7 months. The patched esophagus was removed forgross and microscopic examination, In the second part of the study a segment of the Esophagus was excised in another three groups of dogs and replaced with 3 x 2 cm tubes of Lyodura, Dacron, or PTFE. Here the follow-up was prolonged and included radiological, endoscopic, and histological assessment. The dogs of each subgroup were scheduled to be sacrificed after 6, 8, and12 months. Results indicated that lyophilized dura mater covered and neoepithelialized the patched area within the shortest period of time without foreign body reaction and with only slight collagen deposit, resulting in a ductile repaired esophageal wall. Therefore, its use may be considered for replacement of partial esophageal defects. For complete circumferential defects, the present study and our review of: the literature showed that there is as yet no ideal prosthetic material that promotes good incorporation butis not prone to stenosis. Further studies in this area are required. (C) 1999 John Wiley & Sons, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/01/21 alle ore 23:00:48