Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Comparison between fenoterol and fenoterol plus oxitropium bromide delivered by metered-dose inhaler with InspirEase to relieve acute asthma attack
Autore:
Kamei, T; Fujita, J; Okada, H; Nakamura, H; Kishimoto, T; Momoi, A; Kawaji, K; Yoshinouchi, T; Ueda, N; Takahara, J;
Indirizzi:
Kagawa Prefectural Cent Hosp, Kagawa, Japan Kagawa Prefectural Cent Hosp Kagawa Japan ural Cent Hosp, Kagawa, Japan
Titolo Testata:
JOURNAL OF ASTHMA
fascicolo: 1, volume: 36, anno: 1999,
pagine: 67 - 75
SICI:
0277-0903(1999)36:1<67:CBFAFP>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEBULIZED IPRATROPIUM BROMIDE; ALBUTEROL; EFFICACY;
Keywords:
fenoterol inhalation; oxitropium inhalation; metered-dose inhaler; acute asthma attack;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Fujita, J Kagawa Med Sch, Dept Internal Med 1, 1750-1, Miki, Kagawa 7610793, Japan Kagawa Med Sch 1750-1 Miki Kagawa Japan 7610793 a 7610793, Japan
Citazione:
T. Kamei et al., "Comparison between fenoterol and fenoterol plus oxitropium bromide delivered by metered-dose inhaler with InspirEase to relieve acute asthma attack", J ASTHMA, 36(1), 1999, pp. 67-75

Abstract

Although the inhalation of beta(2)-agonists has frequently been used to relieve acute asthma attacks, the efficacy of anticholinergic agents for acute asthma attacks still remains unclear. This study was designed to compare the inhalation of fenoterol and the inhalation of fenoterol plus oxitropiumbromide delivered by a metered-dose inhaler with holding chamber (InspirEase) to relieve acute asthma attacks. To accomplish this, 69 patients who had presented with an acute asthma attack were randomized to receive either fenoterol (1 puff [200 mu g/puff] every 1 min for 5 min; total 1000 mu g) orfenoterol plus oxitropium bromide (2 puffs [100 mu g/puff] every 1 min for5 min; total 1000 mu g). The peak expiratory flow (PEF) and forced expiratory volume in 1 sec (FEV,) values were measured before treatment, and 1, 15, 30, and 60 min after the inhalation therapy. The ratios of improvement, PEF (or FEV1) after treatment divided by PEF (or FEV1) before treatment, were also calculated. Thirty-th ree patients were evaluated in the combinationgroup and 31 patients were evaluated in the fenoterol group. The PEF valueat 60 min after inhalation therapy of the fenoterol plus oxitropium bromide group (261 +/- 18 L/min, mean +/- standard error) was significantly higher compared to that of the fenoterol group (210 +/- 17 L/min). In addition, the ratios of improvement of PEF at 1, 15, 30, and 60 min after inhalation therapy were significantly higher in the fenoterol plus oxitropium bromide group compared with the fenoterol group.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 04:19:13