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Titolo:
Electron capture versus energetic dissociation of protein ions
Autore:
Kruger, NA; Zubarev, RA; Carpenter, BK; Kelleher, NL; Horn, DM; McLafferty, FW;
Indirizzi:
Cornell Univ, Baker Lab Chem, Ithaca, NY 14850 USA Cornell Univ Ithaca NYUSA 14850 iv, Baker Lab Chem, Ithaca, NY 14850 USA
Titolo Testata:
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
, volume: 183, anno: 1999,
pagine: 1 - 5
SICI:
1387-3806(19990301)183:<1:ECVEDO>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
MULTIPLY-CHARGED IONS; INFRARED MULTIPHOTON DISSOCIATION; TRANSFORM MASS-SPECTROMETRY; IMPACT EXCITATION; LARGE MOLECULES; IONIZATION; SPECTRA;
Keywords:
electron capture dissociation; multiply charged gaseous cations; collisionally activated dissociation; protein sequencing;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: McLafferty, FW Cornell Univ, Baker Lab Chem, Ithaca, NY 14850 USA Cornell Univ Ithaca NY USA 14850 hem, Ithaca, NY 14850 USA
Citazione:
N.A. Kruger et al., "Electron capture versus energetic dissociation of protein ions", INT J MASS, 183, 1999, pp. 1-5

Abstract

The identity of neighboring amino acids has little influence on the dissociation of multiply protonated proteins by electron capture dissociation. Asexceptions, no cleavage occurs on the N-terminal side of Pro, and little on either side of Cys, whereas the C-terminal side of Trp is heavily favored. The neighboring amino acids have a far greater effect on energetic dissociation, making the combined methods promising for the de novo sequencing ofproteins. (C) 1999 Elsevier Science B.V.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 23:20:18