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Titolo:
Validation of the Rockall risk scoring system in upper gastrointestinal bleeding
Autore:
Vreeburg, EM; Terwee, CB; Snel, P; Rauws, EAJ; Bartelsman, JFWM; van der Meulen, JHP; Tytgat, GNJ;
Indirizzi:
Univterdam,dam, Acad Med Ctr, Dept Clin Epidemiol & Biostat, NL-1100 DE Ams Univ Amsterdam Amsterdam Netherlands NL-1100 DE Biostat, NL-1100 DE Ams Acad Med Ctr, Dept Gastroenterol & Hepatol, Amsterdam, Netherlands Acad Med Ctr Amsterdam Netherlands ol & Hepatol, Amsterdam, Netherlands Slotervaart Hosp, Dept Gastroenterol, Slotervaart, Netherlands SlotervaartHosp Slotervaart Netherlands erol, Slotervaart, Netherlands
Titolo Testata:
GUT
fascicolo: 3, volume: 44, anno: 1999,
pagine: 331 - 335
SICI:
0017-5749(199903)44:3<331:VOTRRS>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
PEPTIC-ULCER; ENDOSCOPIC THERAPY; HEMORRHAGE; MORTALITY; AREA;
Keywords:
upper gastrointestinal bleeding; risk scoring; prognostic factors; rebleeding; mortality;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Terwee, CB Univ1100terdam, Acad Med Ctr, Dept Clin Epidemiol & Biostat, POB 22700, NL- Univ Amsterdam POB 22700 Amsterdam Netherlands NL-1100 DE NL-
Citazione:
E.M. Vreeburg et al., "Validation of the Rockall risk scoring system in upper gastrointestinal bleeding", GUT, 44(3), 1999, pp. 331-335

Abstract

Background-Several scoring systems have been developed to predict the riskof rebleeding or death in patients with upper gastrointestinal bleeding (UGIB). These risk scoring systems have not been validated in a new patient population outside the clinical context of the original study. Aims-To assess internal and external validity of a simple risk scoring system recently developed by Rockall and coworkers. Methods-Calibration and discrimination were assessed as measures of validity of the scoring system. Internal validity was assessed using an independent, but similar patient sample studied by Rockall and coworkers, after developing the scoring system (Rockall's validation sample). External validity was assessed using patients admitted to several hospitals in Amsterdam (Vreeburg's validation sample). Calibration was evaluated by a chi(2) goodness of fit test, and discrimination was evaluated by calculating the area underthe receiver operating characteristic (ROC) curve. Results-Calibration indicated a poor fit in both validation samples for the prediction of rebleeding (p < 0.0001, Vreeburg; p = 0.007, Rockall), but a better fit for the Amsterdam, The Netherlands prediction of mortality in both validation samples (p = 0.2, Vreeburg; p = 0.3, Rockall). The areas under the ROC curves were rather low in both validation samples for the prediction of rebleeding (0.61, Vreeburg; 0.70, Rockall), but higher for the prediction of mortality (0.73, Vreeburg; 0.81, Rockall). Conclusions-The risk scoring system developed by Rockall and coworkers is a clinically useful scoring system for stratifying patients with acute UGIBinto high and low risk categories for mortality. For the prediction of rebleeding, however, the performance of this scoring system was unsatisfactory.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 22:09:43