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Titolo:
Aortic pressure-diameter relationship assessed by intravascular ultrasound: experimental validation in dogs
Autore:
Hardt, SE; Just, A; Bekeredjian, R; Kubler, W; Kirchheim, HR; Kuecherer, HF;
Indirizzi:
Univ Heidelberg, Inst Physiol 1, D-69125 Heidelberg, Germany Univ Heidelberg Heidelberg Germany D-69125 , D-69125 Heidelberg, Germany Univ Heidelberg, Dept Cardiol, D-69115 Heidelberg, Germany Univ Heidelberg Heidelberg Germany D-69115 , D-69115 Heidelberg, Germany
Titolo Testata:
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
fascicolo: 3, volume: 45, anno: 1999,
pagine: H1078 - H1085
SICI:
0363-6135(199903)45:3<H1078:APRABI>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; SYSTOLIC HYPERTENSION; WALL STIFFNESS; DISTENSIBILITY; CATHETER; INVITRO;
Keywords:
aortic compliance; vascular ultrasound;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Hardt, SE Univnyeidelberg, Dept Cardiol, Bergheimer Str 58, D-69115 Heidelberg, Germa Univ Heidelberg Bergheimer Str 58 Heidelberg Germany D-69115 ma
Citazione:
S.E. Hardt et al., "Aortic pressure-diameter relationship assessed by intravascular ultrasound: experimental validation in dogs", AM J P-HEAR, 45(3), 1999, pp. H1078-H1085

Abstract

Intravascular ultrasound (IVUS) has emerged as an important diagnostic method for evaluating vessel diameter and vessel wall motion. To evaluate the validity of NUS in assessing changes in the pressure-diameter relationship we compared measurements of abdominal aortic diameters derived from IVUS with those simultaneously obtained at the same site using implanted sonomicrometers in five chronically instrumented conscious dogs and in seven acutelyinstrumented anesthetized dogs. Five hundred eighty beats were analyzed toobtain peak systolic and end-diastolic diameters and to calculate aortic compliance at different blood pressure levels induced either by an aortic pneumatic cuff or by intravenous injections of nitroglycerin or norepinephrine. IVUS agreed closely with sonomicrometer measurements at different blood pressure levels. However, IVUS slightly but significantly underestimated aortic diameters by 0.6 +/- 0.7 mm for systolic diameters (P < 0.001) and by 0.7 +/- 0.6 mm for diastolic diameters (P < 0.001) compared with the sonomicrometer measurements. We conclude that IVUS is a feasible and reliable method to measure dynamic changes in aortic dimensions and has the potential to provide ready access to assess aortic compliance in humans.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 08:39:37