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Titolo:
Prevalence and risk factors for abdominal aortic aneurysms in older adultswith and without isolated systolic hypertension
Autore:
Naydeck, BL; Sutton-Tyrrell, K; Schiller, KD; Newman, AB; Kuller, LH;
Indirizzi:
UnivSAittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA 15261 U Univ Pittsburgh Pittsburgh PA USA 15261 Epidemiol, Pittsburgh, PA 15261 U
Titolo Testata:
AMERICAN JOURNAL OF CARDIOLOGY
fascicolo: 5, volume: 83, anno: 1999,
pagine: 759 - 764
SICI:
0002-9149(19990301)83:5<759:PARFFA>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXTREMITY ARTERIAL-DISEASE; SCREENING-PROGRAM; ATHEROSCLEROSIS; GROWTH;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Naydeck, BL Univrgh,tsburgh, Grad Sch Publ Hlth, Dept Epidemiol, 130 DeSoto St, Pittsbu Univ Pittsburgh 130 DeSoto St Pittsburgh PA USA 15261 Pittsbu
Citazione:
B.L. Naydeck et al., "Prevalence and risk factors for abdominal aortic aneurysms in older adultswith and without isolated systolic hypertension", AM J CARD, 83(5), 1999, pp. 759-764

Abstract

An association between abdominal aortic aneurysm (AAA) and atheroscleroticdisease has been recognized and may be due to shared risk factors. A consistent relation between blood pressure and AAA has not been found, AAA was compared between those with and without isolated systolic hypertension (ISH)and prevalence of aortic atherosclerosis wets evaluated. Abdominal aortic ultrasound was performed in 266 people, 143 with ISH and 123 age-similar controls. AAA was defined as an infrarenal aortic diameter of greater than orequal to 3.0 cm or on infrarenal-to-suprarenal diameter ratio of greater than or equal to 1.2. The average age of participants was 73 years. Overall prevalence of AAA was 9.4%, 11.9% in those with ISH and 6.5% among normotensives (p = 0.134). Multivariate analysis revealed male gender (p <0.001), higher low-density lipoprotein (p <0.001), higher pulse pressure (p = 0.032), and current smoking (p = 0.012) to be independent predictors of AAA. Whenevaluating aortic atherosclerosis, those with AAA had significantly largerdiameters of the iliac arteries along with greater intima-media thickness of the iliac arteries. Those with and without aneurysms had a similar prevalence of plaque (89% to 96%), but measured plaques tended to be larger among those with than without AAA (p <0.001). Progression of AAA after 1 year was observed in 8 participants, with a mean diameter change of 3.42 mm. AAA was found to be independently associated with pulse pressure but not with systolic blood pressure. Patients with AAA also had greater wall thickness and greater diameter of the iliac arteries, which are probably associated with the underlying disease process. (C)1999 by Excerpta Medica, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 21:45:32