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Titolo:
Maintenance of blood pressure control and left ventricular performance with small doses of enalapril
Autore:
Gonzalez-Juanatey, JR; Reino, AR; Garcia-Acuna, JM; Gonzalez-Juanatey, C; Valdes, L; de la Pena, MG; Cabezas-Cerrato, J;
Indirizzi:
Complexotela, Univ Santiago de Compostela, Dept Cardiol, Santiago De Compos Complexo Hosp Univ Santiago de Compostela Santiago De Compostela Spain Complexoostela,niv Santiago de Compostela, Hypertens Unit, Santiago De Comp Complexo Hosp Univ Santiago de Compostela Santiago De Compostela Spain
Titolo Testata:
AMERICAN JOURNAL OF CARDIOLOGY
fascicolo: 5, volume: 83, anno: 1999,
pagine: 719 - 723
SICI:
0002-9149(19990301)83:5<719:MOBPCA>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
SMALL ARTERY STRUCTURE; QT DISPERSION; SUDDEN-DEATH; HYPERTENSION; HYPERTROPHY; MASS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Gonzalez-Juanatey, JR Hosp Xeral de Galicia, Dept Cardiol, Santiago De Compostela 15705, Spain Hosp Xeral de Galicia Santiago De Compostela Spain 15705
Citazione:
J.R. Gonzalez-Juanatey et al., "Maintenance of blood pressure control and left ventricular performance with small doses of enalapril", AM J CARD, 83(5), 1999, pp. 719-723

Abstract

Enalapril treatment (20 mg every 12 hours) of 24 patients with essential hypertension and left ventricular (LV) hypertrophy established normal blood pressure (BP) after 8 weeks, and after 7 years had reduced LV mass index by39% from 148 +/- 34 to 90 +/- 16 g/m(2), and had normalized LV structure and function and QT dispersion. Stepwise reduction of the enalapril dosage from 40 to 30, 20, 10, and 5 mg/day during the eighth year caused no significant changes in BP, LV structure, LV systolic function, or QT dispersion, which all likewise remained unaltered during a further year of the 5-mg/day regimen. We conclude that for hypertensive patients in whom prolonged treatment with standard doses of enalapril has normalized BP, LV structure and function, and QT dispersion, significantly smaller doses are sufficient to maintain these cardiovascular achievements. (C)1999 by Excerpta Medica, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 20:04:26