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Titolo:
Uveal melanoma: Correlation of histopathologic and radiologic findings by using thin-section MR imaging with a surface coil
Autore:
Lemke, AJ; Hosten, N; Bornfeld, N; Bechrakis, NE; Schuler, A; Richter, M; Stroszczynski, C; Felix, R;
Indirizzi:
Humboldt3353v, Fak Med, Univ Klinikum Charite, Strahlenklin & Poliklin, D-1 Humboldt Univ Berlin Germany D-13353 arite, Strahlenklin & Poliklin, D-1 Univ Essen Gesamthsch, Augenklin, D-4300 Essen 1, Germany Univ Essen Gesamthsch Essen Germany 1 Augenklin, D-4300 Essen 1, Germany Klinikum Benjamin Franklin, Augenklin & Poliklin, Berlin, Germany KlinikumBenjamin Franklin Berlin Germany n & Poliklin, Berlin, Germany
Titolo Testata:
RADIOLOGY
fascicolo: 3, volume: 210, anno: 1999,
pagine: 775 - 783
SICI:
0033-8419(199903)210:3<775:UMCOHA>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTRAOCULAR TUMORS; METASTATIC CARCINOMA; MALIGNANT MELANOMAS; COMPUTED-TOMOGRAPHY; SIMULATING LESIONS; CONTINUING DILEMMA; PROGNOSTIC FACTORS; OPTIC-NERVE; MANAGEMENT; EYE;
Keywords:
eye, MR; eye, neoplasms; magnetic resonance (MR), surface coils; magnetic resonance (MR), tissue characterization; melanoma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Lemke, AJ Humboldtpusiv, Fak Med, Univ Klinikum Charite, Strahlenklin & Poliklin, Cam Humboldt Univ Campus Virchow Klinikum,Augustenburger Pl 1 Berlin Germany D-13353
Citazione:
A.J. Lemke et al., "Uveal melanoma: Correlation of histopathologic and radiologic findings by using thin-section MR imaging with a surface coil", RADIOLOGY, 210(3), 1999, pp. 775-783

Abstract

PURPOSE: To evaluate whether the different signal intensities at magnetic resonance (MR) imaging of melanoma are associated with a higher content of melanin. MATERIALS AND METHODS: In a prospective study, MR imaging and ophthalmoscopic examination findings in 42 patients (19 women, 23 men; age range, 30-87years) with uveal melanoma were compared with histopathologic examination findings obtained after enucleation. MR imaging was performed with 2-mm sections by using a 5-cm surface toil. T1- and T2-weighted images were obtained before and after contrast material administration. RESULTS: In 33 (79%) of the patients, there was homogeneous tumor pigmentation, whereas in nine (21%) patients, there was inhomogeneous bipartite tumor pigmentation. Compared with the histopathologic data, the results of qualitative evaluation were accurate in 29 (58%) of 50 and in 26 (53%) of 49 tumorous areas on T1- and T2-weighted images, respectively. Quantitative evaluation yielded better results, especially at T1-weighted imaging; an 86% correlation was found. Because of methodological reasons, only the superficial pigmentation of inhomogeneous tumors could be evaluated with ophthalmoscopy. CONCLUSION: Thin-section MR imaging of the eye enables an accurate prediction of melanomatous pigmentation with quantitative evaluation of plain T1-weighted images and is superior to ophthalmoscopy in cases of inhomogeneous pigmentation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/04/20 alle ore 12:03:57