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Titolo:
Frameless stereotactic-directed tissue sampling during surgery of suspected low-grade gliomas to avoid histological undergrading
Autore:
Roessler, K; Czech, T; Dietrich, W; Ungersboeck, K; Nasel, C; Hainfellner, JA; Koos, WT;
Indirizzi:
Univ Vienna, Sch Med, Neurosurg Clin, Vienna, Austria Univ Vienna ViennaAustria na, Sch Med, Neurosurg Clin, Vienna, Austria Univ Vienna, Sch Med, Dept Neuroradiol, Vienna, Austria Univ Vienna Vienna Austria , Sch Med, Dept Neuroradiol, Vienna, Austria Univ Vienna, Sch Med, Inst Neurol, Vienna, Austria Univ Vienna Vienna Austria ienna, Sch Med, Inst Neurol, Vienna, Austria
Titolo Testata:
MINIMALLY INVASIVE NEUROSURGERY
fascicolo: 4, volume: 41, anno: 1998,
pagine: 183 - 186
SICI:
0946-7211(199812)41:4<183:FSTSDS>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL HEMISPHERES; CLINICAL-EXPERIENCE; TUMORS;
Keywords:
low-grade gliomas; frameless stereotactic biopsy; glioma grading; cytological smears;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Roessler, K UnivaVienna, Sch Med, Neurosurg Clin, Waehringer Guertel 18, Vienna, Austri Univ Vienna Waehringer Guertel 18 Vienna Austria nna, Austri
Citazione:
K. Roessler et al., "Frameless stereotactic-directed tissue sampling during surgery of suspected low-grade gliomas to avoid histological undergrading", MIN IN NEUR, 41(4), 1998, pp. 183-186

Abstract

Detection of anaplastic tumor foci for precise grading of gliomas is crucial for prognostic assessment and appropriate postoperative treatment planning. To avoided under-grading in large suspected low-grade gliomas, we employed frameless sterotaxy during open surgery for tissue sampling of radiologically suspected anaplastic foci. In nine patients (mean age 44 years, range 10-67) with large supratentorial suspected low-grade gliomas (32.4 ccm mean vol, range 17.9-68.6 ccm) with small contrast enhancing areas (7.7% meanof total volume, range 0.7-15.3%), a neuronavigation system with a pointerdevice (Easy Guide System Philips) or a navigating microscope (MKM System Zeiss) was used to target small enhancing tumor parts for cytological investigation during open surgery. Consecutive cytological smears revealed anaplastic tumor foci in all patients, correlating with neuroradiologically demonstrated small contrast enhancing areas, although biopsies from all other tumor parts showed low-grade tumors. Final neuropathological diagnosis confirmed anaplasia within the neuroradiologically suspected low-grade gliomas in all patients (2 grade IV, 5 WHO grade III and 2 grade II-III tumors, WHO classification). In our experience frameless stereotactic-directed intraoperative tissue sampling during open surgery of large suspected low-grade gliomas helps to identify small anaplastic areas in mostly large low-grade tumors, and therefore, permits optimum planning of postoperative treatment.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 10:03:52