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Titolo:
Prevalence and correlates of the insulin resistance syndrome among Native Americans - The Inter-Tribal Heart Project
Autore:
Greenlund, KJ; Valdez, R; Casper, ML; Rith-Najarian, S; Croft, JB;
Indirizzi:
Ctrvasc Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Cardio Ctr Dis Control & Prevent Atlanta GA USA 30341 vent & Hlth Promot, Cardio Ctrults Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Div Ad Ctr Dis Control & Prevent Atlanta GA USA 30341 vent & Hlth Promot, Div Ad Ctrabet Control & Prevent, Natl Ctr Chron Dis Prevent & Hlth Promot, Div Di Ctr Dis Control & Prevent Atlanta GA USA 30341 vent & Hlth Promot, Div Di Indiana Hlth Serv, Bemidji Area Off, Bemidji, MN USA Indiana Hlth Serv Bemidji MN USA Serv, Bemidji Area Off, Bemidji, MN USA
Titolo Testata:
DIABETES CARE
fascicolo: 3, volume: 22, anno: 1999,
pagine: 441 - 447
SICI:
0149-5992(199903)22:3<441:PACOTI>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
DISEASE RISK-FACTORS; CARDIOVASCULAR-DISEASE; BLOOD-PRESSURE; METABOLIC SYNDROME; DIABETES-MELLITUS; PIMA-INDIANS; SYNDROME-X; HYPERINSULINEMIA; OBESITY; HYPERTENSION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Greenlund, KJ Ctrvasc Control & Prevent, Natl Ctr Chron Dis Prevent & HlthPromot, Cardio Ctr Dis Control & Prevent 4770 Buford Hwy NE,Mailstop K-45 Atlanta GA USA 30341
Citazione:
K.J. Greenlund et al., "Prevalence and correlates of the insulin resistance syndrome among Native Americans - The Inter-Tribal Heart Project", DIABET CARE, 22(3), 1999, pp. 441-447

Abstract

OBJECTIVE - The clustering of factors characterizing the insulin resistance syndrome has not been assessed among Native Americans, a population at high risk for diabetes and cardiovascular disease. We examined the distribution and correlates of the insulin resistance syndrome among individuals in three Chippewa and Menominee communities in Wisconsin and Minnesota. RESEARCH DESIGN AND METHODS - Cross-sectional data from 488 men and 822 women ages greater than or equal to 25 years in the Inter-Tribal Heart Project (1992-1994) were included. The clustering of each individual trait (hypertension, diabetes, high triglycerides, and low HDL cholesterol) with the other traits and the association of the number of traits with measures of adiposity and insulin levels were examined. RESULTS - Among the men, 40.4, 32.6, 17.4, and 9.6% had none, one, two, orat least three of the four traits, respectively, among the women, the respective percentages were 53.2, 25.6, 15.3, and 6.0%. The percentage of individuals with each particular trait significantly increased (P < 0.01) among those with none, one, or at least two other syndrome traits. Having more syndrome traits was significantly related (P < 0.001) to higher BMI, conicityindex, waist circumference, and waist-to-hip and waist-to-thigh ratios. Among individuals with normal glucose levels, having more syndrome traits wassignificantly related (P less than or equal to 0.05) to higher fasting insulin levels after adjusting for age and measures of adiposity, although associations were attenuated with adjustment for either BMI or waist circumference. CONCLUSIONS - Traits characterizing the insulin resistance syndrome were found to be clustered to a significant degree among Native Americans in thisstudy Comprehensive public health efforts are needed to reduce adverse levels of these risk factors in this high-risk population.

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Documento generato il 05/07/20 alle ore 10:07:43