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Titolo:
Topology of recombinant rat upstream binding factor
Autore:
Ridsdale, RA; Semotok, JL; Larson, DE; Rothblum, LI; Harauz, G;
Indirizzi:
Univ Guelph, Dept Mol Biol & Genet, Guelph, ON N1G 2W1, Canada Univ Guelph Guelph ON Canada N1G 2W1 & Genet, Guelph, ON N1G 2W1, Canada Weis Ctr Res, Geisinger Clin, Danville, PA 17822 USA Weis Ctr Res Danville PA USA 17822 Geisinger Clin, Danville, PA 17822 USA
Titolo Testata:
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE
fascicolo: 4, volume: 76, anno: 1998,
pagine: 649 - 655
SICI:
0829-8211(1998)76:4<649:TORRUB>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
RNA-POLYMERASE-I; RIBOSOMAL GENE-TRANSCRIPTION; FACTOR UBF; NUCLEOPROTEIN STRUCTURES; DIMERIZATION DOMAIN; IMAGE-ANALYSIS; RDNA PROMOTER; PROTEIN HMG1; FACTOR HUBF; DNA;
Keywords:
upstream binding factor; transmission electron microscopy; RNA polymerase I transcription factor; single particle electron crystallography; molecular modelling;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
45
Recensione:
Indirizzi per estratti:
Indirizzo: Harauz, G Univ Guelph, Dept Mol Biol & Genet, Guelph, ON N1G 2W1, Canada Univ Guelph Guelph ON Canada N1G 2W1 Guelph, ON N1G 2W1, Canada
Citazione:
R.A. Ridsdale et al., "Topology of recombinant rat upstream binding factor", BIOC CELL B, 76(4), 1998, pp. 649-655

Abstract

Transmission electron microscopy and single particle electron crystallography were employed to reconstruct high-quality projection images of a recombinant, acidic tail deficient form of rat upstream binding factor. The upstream binding factor was found to be dimeric and approximately 10 nm in diameter with a central region of low density. Distinct nodes were observable, of size and spacing consistent with being HMG boxes 3 and 4. The dimerisation domain seemed most probably to be located in the internal region of the structure.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 14:59:40