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Titolo:
Dynamic imaging and tracer kinetic modeling for emission tomography using rotating detectors
Autore:
Lau, CH; Feng, D; Hutton, BF; Lun, DPK; Su, WC;
Indirizzi:
Hong Kong Polytech Univ, Dept Elect & Informat Engn, Ctr Multimedia Digital Hong Kong Polytech Univ Hong Kong Hong Kong ngn, Ctr Multimedia Digital Univ,Sydney, Basser Dept Comp Sci, Biomed & Multimedia Informat Technol Grp Univ Sydney Sydney NSW Australia 2006 d & Multimedia Informat Technol Grp Westmead Hosp, Dept Phys Med, Westmead, NSW 2145, Australia Westmead HospWestmead NSW Australia 2145 , Westmead, NSW 2145, Australia
Titolo Testata:
IEEE TRANSACTIONS ON MEDICAL IMAGING
fascicolo: 6, volume: 17, anno: 1998,
pagine: 986 - 994
SICI:
0278-0062(199812)17:6<986:DIATKM>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL METABOLIC-RATE; INPUT FUNCTION; COMPUTER-SIMULATION; INTEGRATION METHOD; PET; SPECT; TIME; GLUCOSE; PARAMETERS;
Keywords:
coincidence detection; emission tomography; PET; SPECT; tracer kinetic modeling;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Engineering, Computing & Technology
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Feng, D Hong Kong Polytech Univ, Dept Elect & Informat Engn, Ctr Multimedia Digital Hong Kong Polytech Univ Hong Kong Hong Kong Multimedia Digital
Citazione:
C.H. Lau et al., "Dynamic imaging and tracer kinetic modeling for emission tomography using rotating detectors", IEEE MED IM, 17(6), 1998, pp. 986-994

Abstract

When performing dynamic studies using emission tomography the tracer distribution changes during acquisition of a single set of projections. This is particularly true for some positron emission tomography (PET) systems which, like single photon emission computed tomography (SPECT), acquire data over a limited angle at any time, with full projections obtained by rotation of the detectors. In this paper, an approach is proposed for processing datafrom these systems, applicable to either PET or SPECT. A method of interpolation, based on overlapped parabolas, is used to obtain an estimate of the total counts in each pixel of the projections for eachrequired frame-interval, which is the total time to acquire a single complete set of projections necessary for reconstruction. The resultant projections are reconstructed using traditional filtered backprojection (FBP) and tracer kinetic parameters are estimated using a method which relies on counts integrated over the frame-interval rather than instantaneous values. Simulated data were used to illustrate the technique's capabilities with noise levels typical of those encountered in either PET or SPECT, Dynamic datasets were constructed, based on kinetic parameters for fluoro-deoxy-glucose (FDG) and use of either a full ring detector or rotating detector acquisition. For the rotating detector, use of the interpolation scheme provided reconstructed dynamic images with reduced artefacts compared to unprocessed dataor use of linear interpolation, Estimates for the metabolic rate of glucose had similar bias to those obtained from a full ring detector.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/07/20 alle ore 04:14:09