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Titolo:
Age-related changes in the brainstem auditory evoked potentials of the marmoset
Autore:
Harada, T; Tokuriki, M; Tanioka, Y;
Indirizzi:
Yamaguchi Univ, Fac Agr, Dept Vet Med, Yamaguchi 7538581, Japan Yamaguchi Univ Yamaguchi Japan 7538581 Vet Med, Yamaguchi 7538581, Japan Cent Inst Expt Anim, Miyamae Ku, Kanagawa 2160001, Japan Cent Inst Expt Anim Kanagawa Japan 2160001 e Ku, Kanagawa 2160001, Japan
Titolo Testata:
HEARING RESEARCH
fascicolo: 1-2, volume: 128, anno: 1999,
pagine: 119 - 124
SICI:
0378-5955(199902)128:1-2<119:ACITBA>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
STEM RESPONSE; COMMON MARMOSET; CALLITHRIX-JACCHUS; HEARING-LOSS; STIMULUS-INTENSITY; MONKEY; PRESBYCUSIS; FREQUENCY; KETAMINE; MULATTA;
Keywords:
brain-stem auditory evoked potential; marmoset; aging; stimulus frequency; tone burst stimulation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
42
Recensione:
Indirizzi per estratti:
Indirizzo: Harada, T Mochida268640,ceut, Fuji Cent Res Lab, Div Toxicol, 342 Gensuke,Shizuoka 4 Mochida Pharmaceut 342 Gensuke Shizuoka Japan 4268640 hizuoka 4
Citazione:
T. Harada et al., "Age-related changes in the brainstem auditory evoked potentials of the marmoset", HEARING RES, 128(1-2), 1999, pp. 119-124

Abstract

Changes in brain-stem auditory evoked potentials (BAEPs) with age were recorded in common marmosets (Callithrix jacchus) at the age of 1-2, 6-8 and 10-12 years. The auditory function was assessed by thresholds, latencies andamplitudes of BAEPs evoked by use of tone burst stimulations with audible frequencies ranging from 1 to 99 kHz. Prolongation of the latencies of later waves was observed in the animals at the age of 6-8 and 10-12 years at high frequencies, suggesting that aging in marmosets, as reported previously in humans and other animals, may cause earlier hearing loss at high frequency than at low frequency within the hearing range. At 10-12 years of age, the elevations of BAEP thresholds and the declines of BAEP amplitudes in older animals were also observed. As the differences in the parameters are small, it was suggested that only a moderate hearing loss occurred with onset late in life in common marmoset similar to that in CBA/Ca mice. Based on the results obtained in this study, BAEP latencies appear to be more sensitive indicators than BAEP thresholds and amplitudes for the early detection ofhearing impairment. (C) 1999 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/02/20 alle ore 15:09:07