Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Survival and prognostic factors of invasive aspergillosis after allogeneicbone marrow transplantation
Autore:
Ribaud, P; Chastang, C; Latge, JP; Baffroy-Lafitte, L; Parquet, N; Devergie, A; Esperou, H; Selimi, F; Rocha, V; Derouin, F; Socie, G; Gluckman, E;
Indirizzi:
HopParasitol, Serv Hematol Greffe Moelle, Dept Biostat & Med Informat, LabHop St Louis Paris France F-75475 elle, Dept Biostat & Med Informat, Lab Inst Pasteur, Lab Aspergillus, Paris, France Inst Pasteur Paris FranceInst Pasteur, Lab Aspergillus, Paris, France
Titolo Testata:
CLINICAL INFECTIOUS DISEASES
fascicolo: 2, volume: 28, anno: 1999,
pagine: 322 - 330
SICI:
1058-4838(199902)28:2<322:SAPFOI>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
PULMONARY ASPERGILLOSIS; NEUTROPENIC PATIENTS; FUNGAL INFECTION; GAMMA-INTERFERON; ACUTE-LEUKEMIA; RISK-FACTORS; RECIPIENTS; GLUCOCORTICOIDS; PROPHYLAXIS; MANAGEMENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Ribaud, P HopParasitol, Serv Hematol Greffe Moelle, Dept Biostat & Med Informat, Lab Hop St Louis 1 Ave Claude Vellefaux Paris France F-75475 t, Lab
Citazione:
P. Ribaud et al., "Survival and prognostic factors of invasive aspergillosis after allogeneicbone marrow transplantation", CLIN INF D, 28(2), 1999, pp. 322-330

Abstract

To determine prognostic factors for survival in bone marrow transplant recipients with invasive aspergillosis (IA), we retrospectively reviewed 27 IAcases observed in our bone marrow transplantation unit between January 1994 and October 1994, On 30 September 1997, six patients were alive and disease-free. The median survival after IA diagnosis was 36 days. Of eight variables found to be related to survival according to the univariate analysis, graft-versus-host disease (GVHD) status at IA diagnosis (P = .0008) and thecumulative prednisolone dose taken during the week preceding IA diagnosis (CPD1w) (P < .0001) were selected by a backward stepwise Cox regression model. A three-stage classification was established: CPD1w of less than or equal to 7 mg/kg (3 of 8 patients died; 60-day survival rate, 88%), CPD1w of >7 mg/kg and no GVHD (9 of 10 patients died; 60-day survival rate, 20%), andCPD1w of >7 mg/kg and active acute grade 2 or more or extensive chronic GVHD (9 of 9 patients died; 30-day survival rate, 0) (P < .0001).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 16/07/20 alle ore 06:39:31