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Titolo:
The changes in magnetic resonance properties of the fetal lungs: A first result and a potential tool for the noninvasive in utero demonstration of fetal lung maturation
Autore:
Duncan, KR; Gowland, PA; Freeman, A; Moore, R; Baker, PN; Johnson, IR;
Indirizzi:
Univ Nottingham, Dept Obstet & Gynaecol, Nottingham NG7 2RD, England Univ Nottingham Nottingham England NG7 2RD , Nottingham NG7 2RD, England Univndottingham, Dept Phys, Magnet Resonance Ctr, Nottingham NG7 2RD, Engla Univ Nottingham Nottingham England NG7 2RD tr, Nottingham NG7 2RD, Engla
Titolo Testata:
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY
fascicolo: 2, volume: 106, anno: 1999,
pagine: 122 - 125
SICI:
1470-0328(199902)106:2<122:TCIMRP>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
PULMONARY HYPOPLASIA; RATIO; ULTRASOUND;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Duncan, KR Univ Nottingham, City Hosp, Dept Obstet & Gynaecol, Hucknall Rd, Nottingham Univ Nottingham Hucknall Rd Nottingham England NG5 1PB tingham
Citazione:
K.R. Duncan et al., "The changes in magnetic resonance properties of the fetal lungs: A first result and a potential tool for the noninvasive in utero demonstration of fetal lung maturation", BR J OBST G, 106(2), 1999, pp. 122-125

Abstract

Objective To measure magnetic resonance parameters T1 and T2 of the Fetal lungs and investigate the relationship of these parameters to changes in volume and gestation. Design Prospective cross-sectional study. Setting Large teaching hospital in Nottingham and the Magnetic Resonance Centre at the University of Nottingham. Population Normal pregnancies from 20 weeks to term. Methods T1, T2, and lung volume were measured in the fetus using echo-planar magnetic resonance imaging. Main outcome measures The relationship of T1 and T2 to gestational age andlung volume. Results Linear regression demonstrated a significant relationship (P < 0.001) between gestational age and lung volume, TI and T2. There was also a significant relationship between lung volume and T1 and T2 (P < 0.001). Conclusions Relaxation time measurements give additional information to lung volume estimation in the assessment of lung physiology in utero. We havedemonstrated the progressive changes which take place in the fetal lungs between 20 weeks and term. The physiological changes which can be demonstrated with this non-invasive technique may have an important application in the demonstration of fetal lung maturity in a prospective non-invasive manner.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 18:17:23