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Titolo:
Increased automatic spreading activation in healthy subjects with elevatedscores in a scale assessing schizophrenic language disturbances
Autore:
Moritz, S; Andresen, B; Domin, F; Martin, T; Probsthein, E; Kretschmer, G; Krausz, M; Naber, D; Spitzer, M;
Indirizzi:
Univ6Hamburg, Krankenhaus Eppendorf, Klin Psychiat & Psychotherapie, D-2024 Univ Hamburg Hamburg Germany D-20246 n Psychiat & Psychotherapie, D-2024 Univ Ulm Klinikum, Abt Psychiat, Ulm, Germany Univ Ulm Klinikum Ulm Germany Ulm Klinikum, Abt Psychiat, Ulm, Germany
Titolo Testata:
PSYCHOLOGICAL MEDICINE
fascicolo: 1, volume: 29, anno: 1999,
pagine: 161 - 170
SICI:
0033-2917(199901)29:1<161:IASAIH>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEXICAL DECISION TASK; III-R CRITERIA; SCHIZOTYPAL-PERSONALITY; THOUGHT-DISORDER; WORD PRONUNCIATION; FORMAL THOUGHT; BASIC SYMPTOMS; FACILITATION; ATTENTION; INHIBITION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Life Sciences
Citazioni:
67
Recensione:
Indirizzi per estratti:
Indirizzo: Moritz, S Univistrburg, Krankenhaus Eppendorf, Klin Psychiat & Psychotherapie, Martin Univ Hamburg Martinistr 52 Hamburg Germany D-20246 apie, Martin
Citazione:
S. Moritz et al., "Increased automatic spreading activation in healthy subjects with elevatedscores in a scale assessing schizophrenic language disturbances", PSYCHOL MED, 29(1), 1999, pp. 161-170

Abstract

Background. Previous studies on semantic priming have suggested that schizophrenic patients with language disturbances demonstrate enhanced semantic and indirect semantic priming effects relative to controls. However, the interpretation of semantic priming studies in schizophrenic patients is obscured by methological problems and several artefacts (such as length of illness). We, therefore, used a psychometric high-risk approach to test whether healthy subjects reporting language disturbances resembling those of schizophrenics (as measured by the Frankfurt Complaint Questionnaire subscale 'language') display increased priming effects. In addition, the Schizotypal Personality Questionnaire was used to cover symptoms of schizotypal personality. Enhanced priming was expected to occur under conditions favouring automatic processes. Methods. One hundred and sixty healthy subjects performed a lexical decision semantic priming task containing two different stimulus onset asynchronicities (200ms and 700 ms) with two experimental conditions (semantic priming and indirect semantic priming) each. Results. Analyses of variance revealed that the Frankfurt Complaint Questionnaire- 'language' high scorers significantly differed from low scorers inthree of the four priming conditions indicating increased automatic spreading activation. No significant results were obtained for the Schizotypal Personality Questionnaire total and subscales scores. Conclusions. In line with Maher and Spitzer it is suggested that increasedautomatic spreading activation underlies schizophrenia-typical language disturbances which in our study cannot be attributed to confounding variablessuch as different reaction time baselines, medication or length of illness. Finally, results confirm that the psychometric high-risk approach is an important tool for investigating issues relevant to schizophrenia.

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Documento generato il 29/03/20 alle ore 12:14:50