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Titolo:
Role of the prefrontal cortex in the control of express saccades. A transcranial magnetic stimulation study
Autore:
Muri, RM; Rivaud, S; Gaymard, B; Ploner, CJ; Vermersch, AI; Hess, CW; Pierrot-Deseilligny, C;
Indirizzi:
Univ Bern, Inselspital, Dept Neurol, CH-3010 Bern, Switzerland Univ Bern Bern Switzerland CH-3010 ept Neurol, CH-3010 Bern, Switzerland Hop La Pitie Salpetriere, Serv Neurol, F-75651 Paris 13, France Hop La Pitie Salpetriere Paris France 13 eurol, F-75651 Paris 13, France Hop La Pitie Salpetriere, INSERM U289, F-75651 Paris 13, France Hop La Pitie Salpetriere Paris France 13 U289, F-75651 Paris 13, France
Titolo Testata:
NEUROPSYCHOLOGIA
fascicolo: 2, volume: 37, anno: 1999,
pagine: 199 - 206
SICI:
0028-3932(199902)37:2<199:ROTPCI>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
FRONTAL EYE FIELD; SUPERIOR COLLICULUS; CORTICAL CONTROL; GUIDED SACCADES; REACTION-TIME; LATENCY; MONKEY; MOVEMENTS; FIXATION; LESIONS;
Keywords:
human; eye movements; prefrontal cortex; inhibition; TMS; saccades;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Muri, RM Univ Bern, Inselspital, Dept Neurol, CH-3010 Bern, Switzerland Univ Bern Bern Switzerland CH-3010 l, CH-3010 Bern, Switzerland
Citazione:
R.M. Muri et al., "Role of the prefrontal cortex in the control of express saccades. A transcranial magnetic stimulation study", NEUROPSYCHO, 37(2), 1999, pp. 199-206

Abstract

Single pulse transcranial magnet stimulation (TMS) was applied in five subjects during a saccadic gap task, i.e. with a temporal gap of 200 ms between the extinguishing of the central fixation point and the appearance of, the lateral target. In all subjects, a significant increase of contralateral express saccades was found when TMS was applied over the dorsolateral prefrontal cortex (DPFC) at the end of the gap of 200 ms. Earlier stimulation over the DPFC during the gay had no significant effect. Furthermore, stimulation over the posterior parietal cortex with the same time intervals, and stimulation during a no gap task had no significant influence on express saccades. These results suggest that TMS is capable of interfering specificallywith the functioning of the DPFC, probably by inhibition of this region. Possibly such stimulation of the DPFC reduces the inhibition by this region onto the superior colliculus, which results in a facilitation of express saccades. (C) 1999 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 10:04:49