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Titolo:
Therapy-related myelodysplastic syndrome in adults with neurofibromatosis
Autore:
Papageorgio, C; Seiter, K; Feldman, EJ;
Indirizzi:
New York Med Coll, Zalmen A Arlin Canc Inst, Valhalla, NY 10595 USA New York Med Coll Valhalla NY USA 10595 Canc Inst, Valhalla, NY 10595 USA
Titolo Testata:
LEUKEMIA & LYMPHOMA
fascicolo: 5-6, volume: 32, anno: 1999,
pagine: 605 - 608
SICI:
1042-8194(1999)32:5-6<605:TMSIAW>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
MALIGNANT MYELOID DISORDERS; VONRECKLINGHAUSEN NEUROFIBROMATOSIS; BONE-MARROW; LEUKEMIA; CHILDREN; TYPE-1; DELINEATION; KARYOTYPE; NEOPLASMS; DISEASE;
Keywords:
neurofibromatosis; adult; myelodysplastic syndrome; acute myelogenous leukemia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Seiter, K Newla,rk Med Coll, Zalmen A Arlin Canc Inst, Room 250 Munger Pavill, Valhal New York Med Coll Room 250 Munger Pavill Valhalla NY USA 10595 l
Citazione:
C. Papageorgio et al., "Therapy-related myelodysplastic syndrome in adults with neurofibromatosis", LEUK LYMPH, 32(5-6), 1999, pp. 605-608

Abstract

Although an increased risk of hematologic malignancies in children with Neurofibromatosis-1 (NF-1) is well established, whether adults with NF-1 havean increased risk of such malignancies is unclear. We currently describe two adult patients with NF-1 who rapidly developed secondary myelodysplasticsyndromes with abnormalities of chromosome 7 following chemotherapy for AML. We propose that adults with NF-1 also have abnormalities of hematologic progenitor cells.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 08:25:50