Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Multiple sclerosis and the urologist
Autore:
Litwiller, SE; Frohman, EM; Zimmern, PE;
Indirizzi:
Univ Texas, SW Med Ctr, Dept Urol, Dallas, TX 75235 USA Univ Texas DallasTX USA 75235 W Med Ctr, Dept Urol, Dallas, TX 75235 USA Univ Texas, SW Med Ctr, Dept Neurol, Dallas, TX 75235 USA Univ Texas Dallas TX USA 75235 Med Ctr, Dept Neurol, Dallas, TX 75235 USA
Titolo Testata:
JOURNAL OF UROLOGY
fascicolo: 3, volume: 161, anno: 1999,
pagine: 743 - 757
SICI:
0022-5347(199903)161:3<743:MSATU>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
URINARY-TRACT DYSFUNCTION; INTRAVESICAL OXYBUTYNIN CHLORIDE; DETRUSOR-SPHINCTER DYSSYNERGIA; MICTURITION REFLEX PATHWAY; PLACEBO-CONTROLLED TRIAL; ACUTE OPTIC NEURITIS; QUALITY-OF-LIFE; DOUBLE-BLIND; ERECTILE DYSFUNCTION; BLADDER DYSFUNCTION;
Keywords:
multiple sclerosis; urodynamics; bladder, neurogenic;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
181
Recensione:
Indirizzi per estratti:
Indirizzo: Litwiller, SE UnivUSAxas, SW Med Ctr, Dept Urol, 5323 Harry Hines Blvd, Dallas, TX 75235 Univ Texas 5323 Harry Hines Blvd Dallas TX USA 75235 X 75235
Citazione:
S.E. Litwiller et al., "Multiple sclerosis and the urologist", J UROL, 161(3), 1999, pp. 743-757

Abstract

Purpose: We provide an updated reference detailing the neurological and urological state of the art approach to multiple sclerosis (MS) with special emphasis on the pathology and physiology, effects on the genitourinary tract, diagnostic evaluation, and treatment of neurological and urological manifestations. Materials and Methods: A MEDLINE computerized reference search and manual bibliography review were performed to find pertinent peer reviewed articleson the neurological and urological manifestations and treatment of MS. A meta-analysis was performed on the urodynamic findings of 22 studies involving 1,882 patients from well-defined MS populations. Results: The majority of patients with MS have genitourinary symptoms ranging from urgency, urge incontinence and frequency to urinary retention. Symptoms do not accurately reflect the underlying urological pathology but parallel pyramidal tract dysfunction. Urodynamic evaluation has an important role in determining proper bladder management. The most common urodynamic finding is detrusor hyperreflexia in 62% of these patients, followed by detrusorsphincter dyssynergia in 25% and hypocontractility in 20%. Less than 1% of patients has renal deterioration and most may be treated with conservative measures. If conservative measures fail, new forms of bladder reconstruction and diversion may be effectively used. The incidence of sexual dysfunction is up to 80% in men and 72% in women, and treatment focuses on improvement of overall disability and erectile or orgasmic function. Conclusions: Although the genitourinary consequences of MS are rarely lifethreatening, they can cause significant morbidity and patient frustration. With the rapid advances in the medical management of MS the urologist should be actively involved in multispecialty treatment of these patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 03:55:34